abstractparkinson’s disease (pd) is a neuropathological and debilitating disorder involving the degeneration of mesencephalic dopaminergic neurons. neuroprotective effect of hesperetin has already been reported, therefore, this study examined whether the administration of this flavonoid would attenuate behavioral abnormalities in an experimental model of pd in rat. for this purpose, unilateral ...

improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. this process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (hfip) followed by a halogen-exchange fluorination. this is the first synthesis of sev...

a green and convenient protocol is described for the preparation of 1-(alkylamino)-3-(1,3-dioxoisoindolin-2-yl)-2-methyl-1-oxopropan-2-yl benzoates via one-pot three-component reaction between 2-(2-oxopropyl)isoindoline-1,3-dione, an alkyl isocyanide and an aromatic carboxylic acid in water at room temperature. the methods used to follow the reactions are tlc and nmr, which indicated that there...

urinary 1-hydroxypyrene is frequently used as a major metabolite and biological indicator of the overall exposure to polycyclic aromatic hydrocarbons. in this study, solid phase extraction was appropriately conditioned with regard to sample ph, sample concentration, loading flow rate, elution solvent, washing solvent, sample volume and sorbent mass. octadecyl silica cartridge (c18) was used as ...

background and objectives : pseudomonas aeruginosa is one of the most important gram negative opportunistic bacteria which causes infection among burn patients. resistance to the antibiotics in this group of bacteria is increased due to the activity of extended spectrum β-lactamase (esbls) genes. in the current study, we investigated the prevalence of two genes (blaper-1 & blaoxa10) related β-l...

conclusions these results showed that the administration of sdf-1a increases the number of proliferating cells in the injured area in the spinal cord and improves functional recovery. results significant improvements in locomotor function were detected in the sdf-1 group compared with the sci and vehicle groups (p < 0.05). the results showed that sdf-1 treatment increased proliferative cells at...

abstract background: gastric cancer is a life threatening disease. recent studies have shown that rosa damascene possesses noticeable biological effects on the human body. this study, investigates the anticancer effect of rosa damascena on gastric cancer cell line mkn45. methods: microscopic studies and mtt assay were used to examine morphological alteration, and cell survival of the cancer cel...

the most conveni ent me thod f or d e t ermining bone dose duri ng ext ra-oral . radi ogr aphy is ph o togr aph~c r adiation desimetry.this met hod was used bec ause, it is cheap,srnall l i ghtweight a nd adequately sens itive a nd i t a l s o prov i des a p e rmanent r ecor ds ( l o}. i t i s evident f r om thi s r eport tha t a r e l a tionsh i p e xist s between the bone and s k i n dose , a...