BACKGROUND The role of physical trauma in the onset of symptoms in Ehlers-Danlos syndrome (EDS) has never been characterized. We sought to search and describe brain lesions EDS patients also having personal history of physical trauma. We systematically performed brain magnetic resonance imaging in a first cohort of patients with a hypermobility type of EDS which described the onset of their dis...

OBJECTIVE While individuals with insomnia consistently complain of cognitive impairment, previous studies on the effect of insomnia on objective measures of cognitive function have obtained ambiguous results. The relationship between daytime sleepiness and cognitive manifestations in insomnia patients is not clear. METHODS Thirty-six primary insomnia patients (PIPs) and 26 good sleep controls...

The edge dominating set (EDS) and edge cover (EC) problems are classical graph covering problems in which one seeks a minimum cost collection of edges which covers the edges or vertices, respectively, of a graph. We consider the generalized partial cover version of these problems, in which failing to cover an edge, in the EDS case, or vertex, in the EC case, induces a penalty. The objective is ...

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A Somos 4 sequence is a sequence (hn) of rational numbers defined by the quadratic recursion hm+2 hm−2 = λ1 hm+1 hm−1 + λ2 h 2 m for all m ∈ Z for some rational constants λ1, λ2. Elliptic divisibility sequences or EDSs are an important special case where λ1 = h 2 2, λ2 = −h1 h3, the hn are integers and hn divides hm whenever n divides m. Somos (4) is the particular Somos 4 sequence whose coeffi...

BACKGROUND The cross-sectional area of total muscle mass has been reported to decrease by about 40% for those 20-60 years of age. Depressive symptoms may discourage motivation to engage in physical activity such as strength training shown to negate muscle loss. Inflammation related to depressive symptoms may also contribute to muscle atrophy. Physiological differences by sex and race/ethnicity ...

BACKGROUND Difficulty maintaining physician staffing in emergency departments (EDs) prompted the government of Ontario to offer alternate funding arrangements (AFAs) to replace fee-for-service remuneration for physicians working in EDs. OBJECTIVE To analyze the effect of AFAs on physician staffing and practice patterns. METHODS We obtained Ontario Health Insurance Program fee-for-service an...

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