نتایج جستجو برای: oxytocin tgf
تعداد نتایج: 35984 فیلتر نتایج به سال:
BACKGROUND Oxytocin is known to be related to social behaviors, including trust. However, few studies have investigated the association between oxytocin levels and social capital. Thus, we tested the hypothesis that endogenous oxytocin levels are positively associated with social capital. We also considered whether the association differed across gender because previous studies have shown diffe...
AIM Oxytocin produces concentration-dependent relaxation of isolated isthmus and ampulla of human oviduct precontracted by histamine. The aim of our study was to investigate whether this oxytocin effect was specific and by which receptors it was mediated. METHODS We investigated effects of oxytocin and its antagonists on isolated isthmus and ampulla of the uterine tubes from 20 women who unde...
Background: The foremost cause of maternal morbidity and mortality in third-world countries is Post-Partum Hemorrhage (PPH). To prevent PPH, often Misoprostol used. This study aimed to find out the efficacy safety profile when administered rectally comparison oxytocin, avoid incidence PPH. Methods: quasi-experimental on n=72 patients were performed at Ziauddin University Hospital Karachi for 6 ...
[3H]Oxytocin, incubated with rat uterine segments, was bound specifically, and about equally, to the three particulate fractions obtained by homogenization and centrifugation at 1,000, 20,000, and 105,000 X g. There apparently was no binding in the cytosol fraction. [“H]Oxytocin, added directly to rat uterine particles sedimentmg between 1,000 and 20,000 x g, was bound with an apparent & of 1.8...
Synergizing the effect of afferent fibre stimulation with pharmacological interventions is a desirable goal to trigger spinal locomotor activity, especially after injury. Thus, to better understand the mechanisms to optimize this process, we studied the role of the neuropeptide oxytocin (previously shown to stimulate locomotor networks) on network and motoneuron properties using the isolated ne...
Transforming growth factor betas (TGF?s) are one of the most widespread and versatile cytokines. The three mammalian TGF? isoforms, ?1, ?2, and ?3, and their receptors regulate proliferation of neuronal precursors as well as survival and differentiation in neurons of developing and adult nervous system. Functions of TGF?s has a wide spectrum ranging from regulating cell proliferation and differ...
The functional groups in the oxytocin molecule consist, from a chemical standpoint, of a primary amino, a phenolic hydroxyl, three carboxamide groups, and a disulfide linkage. Studies on the relation of structure to biological activity in this and other laboratories have been concerned in part with the significance of these functional groups to the production of a biological response at the sit...
Oxytocin-in-Uniject satisfied the standards of its temperature-time indicator (TTI) in severe home storage conditions, although that required resupply every 30 days-a logistically onerous programmatic standard. Possible advances include: (1) incorporating TTIs with packaged batches of less expensive and more widely used conventional vials of oxytocin; (2) using TTIs calibrated more closely to t...
Oxytocin, a nine amino acid peptide, is highly conserved in placental mammals, including humans. Oxytocin has a physiological role in parturition and parenteral administration of the synthetic peptide is used to induce labor and control postpartum hemorrhage. Endogenous levels of oxytocin before labor are ∼20 pg/mL, but pharmacological administration of the peptide can achieve levels of 110 pg/...
In this study, we determined the projections of oxytocin-containing neurons of the paraventricular nucleus (PVN) to phrenic nuclei and to the rostral ventrolateral medullary (RVLM) region known to be involved in respiratory rhythm generation. Studies were also designed to determine oxytocin receptor expression within the RVLM, and the physiological effects of their activation on respiratory dri...
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