We investigated the effects of the angiotensin-converting enzyme inhibitor captopril on neurologic outcome in a rat model of incomplete cerebral ischemia. Twenty male Sprague-Dawley rats were anesthetized with 70% nitrous oxide in oxygen and fentanyl (10 micrograms x kg-1 i.v. bolus, 25 micrograms x kg-1 x hr-1 i.v. continuous infusion). Animals in group 1 (n = 10) received no angiotensin-conve...

BACKGROUND Optimising the fluid resuscitation of patients with severe malaria is a simple and potentially cost-effective intervention. Current WHO guidelines recommend central venous pressure (CVP) guided, crystalloid based, resuscitation in adults. METHODS Prospectively collected haemodynamic data from intervention trials in Vietnamese adults with severe malaria were analysed retrospectively...

The main effects of three different irrigation regimes, i.e., sustained deficit irrigation (SDI), regulated deficit irrigation (RDI) and non-irrigated (NI), on seed traits namely proanthocyanidins (PAs) were evaluated in the wine grape cultivar Aragonez (syn. Tempranillo) grown in Alentejo (Portugal) over two growing seasons. Results showed that while the number of seeds per berry was not affec...

introduction: prolonged and intermittent oxygen pre-exposure is associated with protection against ischemic reperfusion (ir) injury. in the current study, attempts were made to investigate the relationship between exposure to prolonged and intermittent normobaric hyperoxia (nbho) and expression of excitatory amino acids transporters (eaats) and tnf-α level. method: rats were divided into four m...

UNLABELLED Chronic wounds are an increasing problem in our ageing population and can arise in many different ways. Over the past decades it has become evident that sufficient oxygen supply is an essential factor of appropriate wound healing. Sustained oxygen deficit has a detrimental impact on wound healing, especially for patients with chronic wounds. This has been proven for wounds associated...

It is shown that the anomalous glow observed in the recent space shuttle flights can be attributed to a combination of beam plasma discharge and critical ionization phenomena. While the shuttle velocity (~8 km s -x) is below the critical ionization velocity, which for oxygen is 12.7 km s -x, specular reflection of a small fraction (2-3%) of ambient ions forms an ion beam with velocity 16 km s -...

This is a review of the results reported by studies on the impact of the Tibetan Plateau uplift on the body size, external organs, auditory organ and sexual dimorphism of animals. In high-altitude areas, strong selection pressures, such as low temperature, oxygen deficit, high frequency of strong winds, long periods of animal inactivity, and food shortages, have led to reduction in animal size,...

Menaquinone-7 (MK-7) provides significant health gains due to its excellent pharmacokinetic properties. However, MK-7 occurs at low concentrations in mainstream foods, heightening the demand for nutritional supplements. exists as geometric isomers, and only all-trans is bioactive. Exposure certain environments impacts isomer profile. Knowledge of these factors their influence on composition imp...

Cerebral Protection During Carotid Endarterectomy • Carotid endarterectomy was performed on 73 occasions using the following regimen during the operative period: (1) general anesthesia with normothermia, (2) maintaining a normal or slightly elevated arterial oxygen tension (Pao,, (3) maintaining a normal or low arterial carbon dioxide tension (Pco,), (4) maintaining systemic arterial pressure (...