Torsoni, Adriana S., Priscila M. Fonseca, Daniela P Crosara-Alberto, and Kleber G. Franchini. Early activation of p160ROCK by pressure overload in rat heart. Am J Physiol Cell Physiol 284: C1411–C1419, 2003. First published February 5, 2003; 10.1152/ajpcell.00098.2002.—We investigated the effects of acute pressure overload on activation of p160ROCK in rat myocardium. Constriction of transverse ...

Wireless intelligent network (WIN) is a network in the mobile environment that supports the use of intelligent network capabilities which is mainly made up of a service control point (SCP) and some mobile switching centers (MSCs). When there are too more incoming services to SCP and MSCs in the WIN simultaneously than they can handle will cause the SCP or MSCs overload and degrades the performa...

The aim of the present study was to describe histologic features of the liver in insulin resistance-associated hepatic iron overload (IR-HIO), defined as the association of metabolic disorders and hepatic iron overload. We included 139 patients in the study on the basis of one or more metabolic disorders and liver iron overload unrelated to usual causes. Liver biopsy specimens were reviewed, an...

This research centers on the relationship between information overload as an aspect of information quality on the one side, and, on the other side, user resistance to knowledge management systems as an aspect of an individual’s decision process. While discussing this relationship theoretically we propose a bipartite influence of information overload as on the one hand it fosters acceptance of t...

Disturbances in iron metabolism can be genetic or acquired and accordingly manifest as primary or secondary iron overload state. Organ damage may result from iron overload and manifest clinically as cirrhosis, diabetes mellitus, arthritis, endocrine abnormalities and cardiomyopathy. Hemochromatosis inherited as an autosomal recessive disorder is the most common genetic iron overload disorder. E...

The relative effects of chronic pressure overload and chronic volume overload on left ventricular diastolic chamber stiffness were examined using a combined hemodynamic and ultrasonic technique in 27 patients. The slope of the left ventricular pressure-diameter relation in late diastole was measured and found to be steep in the groups with pressure or volume overload (9.0 ± 1.8 mm Hg/mm for pre...

The Session Initiation Protocol (SIP) server overload management has attracted interest since SIP is being widely deployed in the Next Generation Networks (NGN) as a core signaling protocol. Yet all existing SIP overload control work is focused on SIP-over-UDP, despite the fact that TCP is increasingly seen as the more viable choice of SIP transport. This paper answers the following questions: ...

Currently, hematopoietic stem cell transplantation (HSCT) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful HSCT. Liver biopsy samples were taken from 14 patients (Out of 25 patients) who underwent HSCT. All patients met three criteria: negative HCV antibody...

Chronic pressure overload leads to hypertrophy, depressed mechanical function, and reduced myosin ATPase activity. However, it is not known whether the lowered myosin ATPase activity results from the hypertrophic process per se or whether the elevated afterload is required for the depressed myosin ATPase activity. Further, a causal relationship between lowered myosin ATPase and weakened mechani...

Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic syndrome, can significantly induce injured bone marrow (BM) function as well as parenchyma organ dysfunctions. However, the effect of iron overload and its mechanism remain elusive. In this study, we investigated the effects of ir...