Overactive bladder (OAB) with or without urinary incontinence is a common condition in both men and women. OAB has a significant impact on quality of life for most patients. In most cases, sophisticated testing is not required for a primary care physician to diagnose OAB and start treating a patient. Management of OAB requires behavioral modification and, if necessary, pharmacotherapy may be...

CNS Spectr 13:6 June 2008 467 NEW TREND IN PSYCHOPHARMACOLOGY The hypothalamic-pituitary-adrenal axis is a key mediator of the stress response in humans. The corticotropin-releasing factor (CRF) type 1 receptor (CRFR-1) in the pituitary gland is a gatekeeper for that response, and the CRFR-1 receptor is also present in many other moodand cognition-related neural structures. Behaviorally, a numb...

IN LATE June of 1970, the Wash ington Post reported that doctors in Omaha, Nebraska, were giving hundreds of school children so-called behavior modification drugs to make them "behave" better. Five days later Huntley-Brinkley featured a news story about the Omaha situation on their national news cast. These, as well as other news media, posed some very real concerns about possible misuse of var...

Objective. To assess the efficacy and the effect on Qol of solifenacin for the treatment of OAB in MS patients. Patients and Methods. Thirty MS patients suffering from OAB were treated with solifenacin 5/10 mg for 8 weeks. The first 4 weeks patients received solifenacin 5 mg. At week 4 patients could request a dose increase to 10 mg. The efficacy was evaluated at 8 weeks. Results. After 4 weeks...

Division of Dentistry, Department of Pediatric Surgery, Bambino Gesù Children's Hospital, Piazza Sant’Onofrio n°4, 00146, Rome, Italy Department of Neurosciences, Reproductive Sciences and Oral Sciences, University of Naples "Federico II", Via Pansini n°5, 80131, Naples, Italy Institute of Biochemistry and Clinical Biochemistry, Catholic University of Sacred Heart, Largo Francesco Vito 1, 00168...

Around 1.5% of adults in Europe and the USA have urge urinary incontinence (involuntary leakage immediately preceded or accompanied by urgency) (Abrams 2003; Irwin 2006). This is usually due to overactive bladder syndrome (defined as urgency, with or without urge incontinence, and usually with frequency and nocturia) (Abrams 2003). The symptoms of an overactive bladder are thought to be due to ...

The efficacy of intravesical onabotulinumtoxinA (BTXA) in the treatment of overactive bladder (OAB) has been well documented. The use of BTXA injection in orthotopic neobladders is yet to be studied. We present 4 cases of patients injected with intravesical BTXA for overactive orthotopic ileal neobladder. We recorded patient demographics, presenting and follow-up symptoms, urodynamic profiles, ...

The prevalence of urinary incontinence is around 20% of healthy middle-aged women. Incontinence causes a negative impact on the quality of life and sexuality. From August 2002 to January 2004, 30 patients (mean age 43 years) with stress urinary incontinence (59%), overactive bladder (15%) and mixed incontinence (26%) answered the ICIQ-SF(International Consultation on Incontinence Questionnarie-...

UNLABELLED The AIM of the study was to validate some of the imaging criteria for voiding dysfunction in children. MATERIAL AND METHODS The study included a number of 55 children with voiding dysfunction symptoms. They were investigated clinically as well as through imaging techniques: renourinary ultrasound, voiding cystourethrography and cystometry. RESULTS The most common symptoms were ur...