This review outlines the main features of clinical trials where cultivated oral mucosa epithelial cell transplantation (COMET) was performed, aiming to underscore a link between outcome and expression specific markers during follow-up patients, characteristic for defined epithelium (cornea, mucosa, or conjunctiva) related vascularization. Currently, little is known about reasons underlying succ...

purpose: to report the outcomes of conjunctival-limbal autograft (clau) in patients with unilateral total limbal stem cell deficiency (lscd) emphasizing surgical problems, complications, and their management. methods: in this prospective interventional case series, clau combined with amniotic membrane transplantation as a graft was performed on 26 patients with unilateral total lscd due to chem...

The repair of critical-size bone defects resulted from severe traumatic injury, infection, surgery for bone cancer or congenital malformation remains a continuous challenge for orthopedists. Currently, autogenous bone grafting is a clinical gold standard for bone repair, and provides excellent osteoconduction, osteoinduction, high-healing rate and absence of immunogenic reaction after surgery. ...

the investigation and determination of the significance of neovascularization in the progression of soft tissue sarcoma is currently of increasing clinical importance. microvessel density is the morphologic evidence of neoangiogenesis in the process of malignant progression of sarcomata. this brief review of the markers commonly used in clinical practice was undertaken to determine the validity...

The recent development of high-frequency ultrasound, associated with the improved sensitivity in color Doppler, enabled the identification of various skin structures and layers. In basal cell carcinoma, the 22 MHz frequency ultrasound permits the delimitation of tumor margins, while color Doppler, determines its vascularization. We present two cases in which the association of both exams allowe...