The radiofrequency ablation (RFA) is considered a valid, minimally invasive treatment modality for the management of symptomatic knee osteoarthritis (OA). aim this study was to compare outcomes RFA with that commonly used intra-articular injections persistent pain due OA. Medline/Pubmed and Scopus databases were systematically searched up April 2023 identify studies comparing effect (IAIs) on N...

objective(s): osteoarthritis (oa), as a known degenerative joint disease, is the most common form of arthritis. in this study, we aimed to elucidate unclear pathogenesis of oa. materials and methods: rabbit models of oa were established by the transection of the anterior cruciate ligament. rabbits were randomly divided into three equal groups: the experimental group (oa modeling, treated with e...

  Abstract   Background: Osteoarthritis (OA) is the most common joint disease occuring after middle age. Because of the high mobility of the neck, OA is common in the cervical spine. The purpose of this study was to determine and compare the effects of intermittent traction on patients with mild and moderate cervical OA. Therefore, 32 patients with cervical OA were recruited.   Methods: Aclinic...

Abstract Background Osteoarthritis (OA) is a degenerative disease which presents with joint pain and stiffness reduced mobility. Knee OA the commonest cause of disability in adults. Dextrose prolotherapy new option used to treat mild-to-moderate knee OA. Neural (NPT) multiple small injections under skin targeting painful areas natural substances. The aim work was evaluate compare neural versus ...

1063-4584/$ – see front matter 2011 Osteoarthritis doi:10.1016/j.joca.2011.10.008 The challenge of disease definition in osteoarthritis (OA) continues to grow. As described by Pereira et al., in a recent issue of Osteoarthritis and Cartilage (OAC), there are substantial differences in prevalence and incidence estimates when defining OA by radiographic changes alone, as symptomatic OA (requiring...

abstract   background: osteoarthritis (oa) is the most common joint disease occuring after middle age. because of the high mobility of the neck, oa is common in the cervical spine. the purpose of this study was to determine and compare the effects of intermittent traction on patients with mild and moderate cervical oa. therefore, 32 patients with cervical oa were recruited.   methods: aclinical...

OBJECTIVES To study the impact of articular hypermobility on the clinical and radiological features of hand osteoarthritis (OA) and to investigate whether hand osteoarthritis associated with hypermobility should be considered a separate subset of hand OA. METHODS Fifty consecutive female patients with clinical hand OA and thumb base symptoms were examined for hypermobility according to the Be...

OBJECTIVE To evaluate the association between cigarette smoking and the subsequent development of osteoarthritis (OA) at four separate sites: knee, hand, foot and cervical spine. METHODS This cohort study examined 2505 men and women aged 40 years and older participating in the longitudinal Clearwater Osteoarthritis Study (1988-current). Biennial physical exams, including serial radiographs, a...

Transforming growth factor alpha (TGFα) is a growth factor involved in osteoarthritis (OA). TGFα induces an OA-like phenotype in articular chondrocytes, by inhibiting matrix synthesis and promoting catabolic factor expression. To better understand TGFα's potential as a therapeutic target, we employed two in vivo OA models: (1) post-traumatic and (2) aging related OA. Ten-week old and six-month ...

Osteoarthritis (OA), the most common degenerative joint disease, results from an imbalance between chondrocyte-controlled anabolic and catabolic processes. OA is characterized by progressive degradation of components of the Extracellular Matrix (ECM) within the articular cartilage, correlated with secondary inflammation. Several studies had investigated the morphological and biochemical changes...