a new system is presented for the generation ofrecombinant bacillus subtilis strains without antibioticmarkers. this system is based on two plasmids constructed in escherichia coli. the first plasmid phm30contains an incomplete hisi gene, the last gene in thehistidine biosynthesis operon of b. subtilis and part ofthe genes yvca and yvcb of unkown function flankinghisi at the 3´-end. the spectin...

While the number of computers in the classroom continues to increase and tremendous support for technology integration exists in government, business, and academia, a major discrepancy exists between the level of technology use that is expected from the educators and the actual use and integration of technology in the classroom. However, effective technology integration in early childhood educa...

In this paper, we studied the numerical solution of nonlinear weakly singular Volterra-Fredholm integral equations by using the product integration method. Also, we shall study the convergence behavior of a fully discrete version of a product integration method for numerical solution of the nonlinear Volterra-Fredholm integral equations. The reliability and efficiency of the proposed scheme are...

after the cold war, the concept of international security underwent a modification. among the most important components of such a transformation, the consolidation of ‘environmental security’, a topic in international security, can be taken into account. environmental security deal with threats that are not only the unintentional result of social and economic activities but are very slow in...

in this paper, quadratic rules for obtaining approximate solution of definite integrals as well as single and double integrals using spline quasi-interpolants will be illustrated. the method is applied to a few test examples to illustrate the accuracy and the implementation of the method

the dna microarray is an important technique that allows researchers to analyze many gene expression data in parallel. although the data can be more significant if they come out of separate experiments, one of the most challenging phases in the microarray context is the integration of separate expression level datasets that have gathered through different techniques. in this paper, we present a...

education has stepped to an ultra-place and time in 21st century. we have entered to digital and wireless communication century which mobile technologies have changed the process of education and instruction. the application of these mobile technologies for creation of knowledge, attitude and skill in learners is called mobile learning. the effectiveness of mobile learning programs requires new...

objective the primary problem in children with cerebral palsy (cp), frequently referred for occupational therapy, is gross motor dysfunction. the current study was designed to investigate the effects of sensory integration therapy (sit) on gross motor skills in cp patients. materials & methods twenty-four children with diplegic spastic cp were randomly divided into two groups: first group (n=14...

this paper presents a computational method for solving two types of integro-differential equations, system of nonlinear high order volterra-fredholm integro-differential equation(vfides) and nonlinear fractional order integro-differential equations. our tools for this aims is operational matrices of integration and fractional integration. by this method the given problems reduce to solve a syst...