cancer stem cells (csc) are the tumor-associated cells existed within tumors or hematological cancers which share characteristics similar to normal stem cells. the common characteristics of a normal stem cell and a csc are their differentiation capacity and self-renewal in tumors. the expression pattern of csc markers differs depending on the type and location of cancers. cd molecules are proba...

pancreatic cancer (pc) is a progressive, fatal disease with a high degree of malignancy. more than 40000 peoplediefrom this cancer annually in the united states. as a multifactorial condition, pc has a complex nature, and there are several genes and signalingpathwaysimplicated in pc pathogenesis and progression. there are diffèrent mutations in master genesincludingtumorsuppressors and oncogene...

cancer patients are more susceptible to adverse drug-drug interactions (ddis) due to receiving multiple medications especially chemotherapy medications, hormonal agents and supportive care drugs. the aim of this study is to describe the prevalence of potential ddis and to identify risk factors for these potential interactions in hospitalized cancer patients in a developing country.a cross-secti...

background: in the process of cancer treatment, mothers of children with cancer experience burden of care as a result of these conditions. early detection of burden of care has an important role in promoting health care. the aim of this study was to evaluate burden of care in mothers of children with a malignancy. materials and methods: this cross sectional study was done on 70 mothers of child...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

introduction: transhiatal esophagectomy is a widely accepted approach for palliative resection of subcarinal esophageal cancers. this study was designed to evaluate the necessity of routine thoracostomy tube insertion in this technique.  methods: this descriptive study was conducted on 123 consecutive patients with esophageal cancers undergoing transhiatal esophagectomy from march 2001 to febru...

background: emotional intelligence (eq) is positively associated with mental health and it can have a crucial role in mental disorder therapy by suitable coping mechanisms. the present study aimed to evaluate the relationship of eq with anxiety and depression among the women with breast cancer. subjects and methods: during 2013 and in a cross-sectional study, 98 breast cancer patients (14 to 21...

the application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. in recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. on the other hand, encapsulation of drugs into nanoparticles (nps) can improve...

background: latent adenocarcinoma of prostate refers to cases who present no obvious sign or symptom during their life spans and the tumor is incidentally found at postmortem examination. its frequency can be very important in epidemiologic investigations, prevention and treatment. no previous study has been done in this regard in iran and the studies performed in other countries show various r...

physical agents such as ultraviolet or ionizing radiation and repetitive trauma have been related to the causation of cancer in humans. much less clear is the association between exposure to radiofrequency, such as radar and microwave radiation to the development of cancer. sporadic case reports and small series suggest that this type of radiation might lead to cancer or contribute to its evolu...