OBJECTIVE We hypothesized that differences exist in the effect of apnea severity and those of laryngopharyngeal reflex (LPR) versus gastroesophageal reflex (GER) on arousals during sleep in patients with obstructive sleep apnea syndrome (OSAS). METHODS Japanese patients having witnessed snoring or excessive daytime sleepiness with a frequency scale for symptoms of GER of 10 or more or with vi...

The prevalence of several cardiovascular diseases is increased with obstructive sleep apnoea syndrome (OSAS), due to, as yet, unclear reasons. Angiotensin converting enzyme (ACE) abnormalities have been implicated in the pathogenesis of various cardiovascular diseases. In this study, plasma ACE activity and the distribution of an insertion (I)/deletion (D) polymorphism of the ACE gene were dete...

AIM The main aim of this study was to assess the presence of behavioural disturbances in child with OSAS before and after adenotonsillectomy (AT). BACKGROUND In children adenotonsillar hypertrophy is associated with increased probability of OSAS. Children with OSAS present neurobehavioral disorders like attention deficit and hyperactivity, learning disabilities and daily attitudes due to exce...

The aim of the present study was to evaluate the impact of obstructive sleep apnoea syndrome (OSAS) and the effects of nasal continuous positive airway pressure (CPAP) on circulating ischaemia-modified albumin (IMA) concentrations. The study included 97 newly diagnosed OSAS patients and 30 nonapnoeic controls. Blood samples were obtained in the morning after polysomnography. After 3 months of C...

UNLABELLED Obstructive sleep apnea syndrome (OSAS) is one of the most complex disorders of sleep; it involves several genetic factors that contribute to the phenotype. Serotonin (5-HT) regulates a variety of visceral and physiological functions, including sleep. Gene 5-HTR2A polymorphisms may change the transcription of several receptors in the serotoninergic system, thereby contributing to OSA...

BACKGROUND Obstructive sleep apnea syndrome (OSAS) is a highly prevalent sleep-related disorder that is associated with increased risk of hypertension (HTN) and coronary heart disease. This study aimed to evaluate the correlation between the OSAS and coronary artery disease (CAD) severity. METHODS The cross-sectional study was conducted from September 2012 to December 2013. We enrolled 127 pa...

Objective: Recently few studies have described presence of cervical spine anomalies in obstructive sleep apnoea syndrome (OSAS) patients. It is also reported that some cases of cervical spine pathologies and osteophytes producing obstructive sleep apnea. We aim to investigate the prevalence of facet joint arthrosis and degenerative disc disease (DDD) in cervical spine using computed tomography ...

We would like to comment on the article recently published in CHEST (September 2008) by Vanhecke et al,1 who reported that morbidly obese patients with obstructive sleep apnea syndrome (OSAS) had lower peak oxygen consumption (V̇o2) and slower heart rate recovery than obese patients without OSAS. First, given that fat is a metabolically inactive indexing of peak V̇o2 to body weight in obese patie...

STUDY OBJECTIVES To determine the effect of obesity and sleep apnea on health care expenditure in women over 10 years. DESIGN Retrospective observational study SETTING Tertiary university-based medical center PATIENTS AND CONTROLS Three groups of age-matched women: 223 obese women with OSAS (body mass index: 39.3 +/- 0.6 kg/m2), and from the general population, 223 obese controls (BMI 36....

Background: Before bariatric surgery, diagnosis of OSAS is vital for the prevention both operative and postoperative complications. İn diagnosing OSAS, polysomnography (PSG) gold-standard method, but it cannot be performed on all patients due to cost time limitations. We aimed determine new predictive factors that we can use identify whom will perform PSG.Materials Methods: Preoperative height,...