This paper uses a longitudinal case study of the infusion of new infrared sensor technology at NASA to illustrate limitations of current conceptual models of the innovation process in large bureaucratic organizations. Based on in-depth interviews with key participants, supplemented by a review of project reports, contract archives, publications and press coverage, the paper constructs a detaile...

This paper uses a longitudinal case study of the infusion of new infrared sensor technology at NASA to illustrate limitations of current conceptual models of the innovation process in large bureaucratic organizations. Based on in-depth interviews with key participants, supplemented by a review of project reports, contract archives, publications and press coverage, the paper constructs a detaile...

BACKGROUND Evidence suggests that direct-to-consumer advertising of prescription drugs increases pharmaceutical sales and both helps to avert underuse of medicines and leads to potential overuse. Concern about such advertising has increased recently owing to the withdrawal from the market of heavily advertised drugs found to carry serious risks. Moreover, the Food and Drug Administration (FDA) ...

BACKGROUND The current direct-to-consumer advertising (DTCA) guidelines were developed with print, television, and radio media in mind, and there are no specific guidelines for online banner advertisements. OBJECTIVE This study evaluates how well Internet banner ads comply with existing Food and Drug Administration (FDA) guidelines for DTCA in other media. METHODS A content analysis was per...

To succeed in the global marketplace, companies must reposition themselves to tap the sources of sustainable growth. After failing to connect information technology investments with business performance, successful senior managers today know that ‘effective use of information’ does not equal merely a new IT solution. Instead, business performance can only be improved with an excellence at using...

874 G eorge Francis Tidmarsh was born in Oak Park, Illinois in 1960. He studied for an MD and PhD in Cancer Biology at Stanford University, where he also completed his clinical training in neonatology and pediatric oncology. He has over 20 years experience in the biotechnology industry and has been instrumental in guiding three drugs through the process of FDA approval. Currently CEO of La Joll...

International Journal of Remote Sensing Publication details, including instructions for authors and subscription information: http://www.informaworld.com/smpp/title~content=t713722504 Satellite-based precipitation estimation using watershed segmentation and growing hierarchical self-organizing map Y. Hong ab; Y. -M. Chiang c; Y. Liu d; K. -L. Hsu a; S. Sorooshian a a Center for Hydrometeorology...

In this issue of the European Heart Journal, Calvo et al. present another plea for simplified approaches to clinical trials evaluating cardiovascular therapies. In the interest of disclosure, I note that I work closely with many of the authors of this article. Dr Christopher Granger, in particular, is a long-time collaborator and senior investigator in my own institution. The thesis advanced by...

The Product Quality Research Institute, in conjunction with the Food and Drug Administration, conducted an anonymous, electronic survey of the biological products manufacturing industry inspected by Team Biologics, with emphasis in obtaining industry input on inspection and compliance aspects of program operations. Representatives from all of the product-specific manufacturing industries inspec...

Unlike most other diseases, cancer instils a special fear and “is treated as an evil, invincible predator, not just a disease.” The ability of drug companies to charge very high prices, even when most approved cancer drugs provide little gain for patients, drives much of the research, as desperate patients lead some governments and private insurers to pay whatever companies charge. Officials wi...