BACKGROUND Medical sphincterotomy has gained popularity as a treatment for anal fissure. Calcium channel blockers in topical forms could also be appropriate with low adverse effects. OBJECTIVES This was a prospective randomized controlled trial to compare topical and oral nifedipine in the treatment of chronic anal fissure. PATIENTS AND METHODS A prospective randomized controlled trial was ...

Lisinopril is used to treat hypertension, congestive heart failure and to improve survival after a heart attack. Learn about side effects, interactions and indications. PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their. Identify these contraindicated and dangerous lisinopril oral (P...

diversity, accessibility and reliability are the three main factors governing the adoption of information sources by farmers in rural areas. based on the research hypothesis, the existing knowledge and information delivery system in the agricultural sector, functions far below the ever changing nature and tangible needs of existing farming systems. the main objective in this study is to determi...

Introduction Numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. These channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. In contrast to the sarcoplasmic reticulum + here potassium channels have been clearly ...

abstract background: the aim of this study was to compare the effects of the second- and third-generation oral contraceptives on women’s reproductive sexual function. materials and methods: this randomized, double-blind, placebo-controlled clinical trial was conducted on 82 married women of reproductive age in tehran. samples were randomized into the groups receiving second- and third-generatio...

In this research, the impact of shoulder width and geometry of gas channel with different structures on proton exchange membrane (PEM) has been investigated using numerical method. 3D, non-isothermal was used with single straight channel geometrywhile maintaining the same boundary conditions and reaction area with addition of humidification for anode and cathode. Our study showed that an ellipt...

Episodic ataxia type 2 (EA2) is an autosomal dominant condition characterized by paroxysmal attacks of ataxia, vertigo, and nausea, typically lasting minutes to days in duration. These symptoms can be prevented or significantly attenuated by the oral administration of acetazolamide; however, the mechanism by which acetazolamide ameliorates EA2 symptoms is unknown. EA2 typically results from non...

OBJECTIVE To investigate cardiovascular drug use and hospitalizations attributable to type 2 diabetes from 1 year before until 6 years after the start of oral antidiabetic therapy. RESEARCH DESIGN AND METHODS In this cohort study, 2,584 patients with type 2 diabetes were selected from the PHARMO Record Linkage System, comprising pharmacy records and hospitalizations for all 320,000 residents ...

how to cite this article: derakhshanfar h, modanlookordi m, amini a, shahrami a. a comparative study of the sedative effect of oral midazolam and oral promethazine medication in lumbar puncture. iran j child neurol. 2013 spring;7(2):11-16.   objective lumbar puncture (lp) essentially is a painful and stressful procedure that indicated for diagnosis and therapeutic purposes. one way to reduce th...

introduction: intracellular ph (phi) regulates essentially all aspects of cellular activities. however, it is unknown how endoplasmic reticulum (er) potassium channels sense phi. in this study, we investigate the direct effects of phi on er potassium channels. methods: we used channel incorporation into the bilayer lipid membrane method. l-α-phosphatidylcholine, a membrane lipid, was extracted ...