Candida albicans is one of the most important fungi associated with oral candidiasis and the treatment of this fungi is a serious problem today because of the resistance of these fungi against conventionally used drugs. So, there is an urgent need of alternative antifungal substances especially from the natural sources. The study was conducted to examine the MFC and time kill activity of two st...

BACKGROUND The aim of this study was to evaluate the clinical lesions of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome patients in the oral cavity, head and neck region and to determine their associations with level of immune suppression as measured by the CD4+ count. MATERIALS AND METHODS In a descriptive cross-sectional study, 50 patients with a proven HIV infection...

Introduction: Denture wearingcan causea varietyoflesionsintheoral cavity, butmost of the problems can be prevented with maintaining healthyoral tissue, denture hygiene and follow up after the dentures delivery. The purpose of this study was the evaluation ofinstructional intervention effect on the incidence of oral candidiasis in complete denture wearers, and its association with age, gender an...

Objective: To determine the different oral findings in patients with renal insufficiency, chronic. Methods: A descriptive cross-sectional study was carried out that included 123 individuals who were diagnosed chronic and underwent dialysis treatment at Renal Services Unit of Austro city Cuenca-Ecuador. Once approved by Research Directorate Faculty Dentistry (DIFO) University Cuenca (code UC-DIF...

Purpose Azole antimycotics and nystatin oral solution are used to treat candidiasis. Azoles inhibit cytochrome (CYP) P450-dependent metabolism of warfarin, which could increase the anticoagulant effect warfarin. Nystatin is not expected interfere with warfarin metabolism, but current data conflicting. With this study, we aimed explore potential drug-drug interactions between azole in treatment ...

We have conducted a longitudinal study over a 3-year period to address the point prevalence, microbiological characteristics and antifungal susceptibility patterns of yeast isolates colonizing or infecting the oral cavities of 111 HIV-infected (51 adults, 60 children) and 201 non HIV-infected (109 adults, 92 children) Mexican persons. Regarding the epidemiology of oral candidiasis, Candida albi...

Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT) recipients. Transplant patients are at risk for such invasive fungal infections. The most common invasive fungal infections are invasive candidiasis in the SOT and invasive aspergillosis in the HSCT. In this article, we will discuss the epidemi...

Objective(s): Candidiasis infection caused by Candida albicans has been known as a major problem in patients with immune disorders. The objective of this study was to genotype the C. albicans isolates obtained from oral cavity of patients with positive human immunodeficiency virus (HIV+) with or/and without oropharyngeal candidiasis (OPC). Materials and Methods:A total of 100 C. albicans isolat...

OBJECTIVE To investigate the relationship between the quantity of Candida colonies in saliva and oral candidiasis (OC), as well as to identify the threshold for distinguishing oral candidiasis from healthy carriage. METHODS A diagnostic test was conducted in 197 patients with different oral problems. The diagnosis of OC was established based on clinical features. Whole saliva samples from the...

CD4 cells status of HIV patients provides one of the benchmarks against the progression of HIV/AIDS. Regular investigation of opportunistic infection in HIV patients is one of the major components of HIV/AIDS care and support service. Between October 2007 and May 2008, a cross-sectional analytical study was carried out in Tribhuvan University Teaching Hospital with an objective to find the rela...