نتایج جستجو برای: or chemically

تعداد نتایج: 3563377  

Journal: :Biochemical Society Transactions 2016

Journal: :Communications in Asteroseismology 2009

Journal: :Journal of the Society of Materials Science, Japan 1992

Journal: :Journal of the Royal Society of Medicine 2005

Journal: :Journal of Polymer Science Part A-1: Polymer Chemistry 1968

Journal: :Rocky Mountain Journal of Mathematics 1976

Journal: :Cancer research 1986
D L Stout F F Becker

Chemically induced rat liver nodules and cancers characteristically demonstrate a limited capacity to activate xenobiotics to reactive species mainly because of decreased amounts of cytochrome P-450. These lesions also show enhancement of xenobiotic detoxication by such mechanisms as enzymic conjugation or reduction of cytotoxic species. We recently demonstrated a similar pattern of metabolic a...

Journal: :Bioorganic & medicinal chemistry letters 2009
Julia I Gavrilyuk Ulrich Wuellner Syed Salahuddin Rajib K Goswami Subhash C Sinha Carlos F Barbas

Irreversible chemical programming of monoclonal aldolase antibody (mAb) 38C2 has been accomplished with beta-lactam equipped mono- and bifunctional targeting modules, including a cyclic-RGD peptide linked to either the peptide (D-Lys(6))-LHRH or another cyclic RGD unit and a small-molecule integrin inhibitor SCS-873 conjugated to (D-Lys(6))LHRH. We also prepared monofunctional targeting modules...

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