A 15yearold boy suffered from blunt trauma to the left eyebrow (Figure 1A arrow). Three hours after the trauma, he had a visual acuity (VA) of no light perception (NLP) in the left eye. Relative afferent pupillary defect was positive in the left eye. The intraocular pressure of each eye was 15 mm Hg. Anterior segment examination results were unremarkable. Funduscopic examination results were no...

purpose: to present a case of herpes zoster ophthalmicus (hzo) with consequent posterior ischemic optic neuropathy (pion). case report: a 58-year-old woman with a history of hzo in her right eye which was under treatment presented with loss of vision to no light perception. on examination, positive relative afferent pupillary defect was detected; however the optic disc was normal on ophthalmosc...

Thy-1 is a cell surface protein that is expressed during the differentiation of retinal ganglion cells (RGCs). Optic nerve injury induces progressive loss in the number of RGCs expressing Thy-1. The rate of this loss is fastest during the first week after optic nerve injury and slower in subsequent weeks. This study was undertaken to determine whether oral treatment with a water-soluble N-hydro...

purpose: to compare the effect of high dose intravenous corticosteroid therapy with placebo in the treatment of recent traumatic optic neuropathy (ton). methods: in a double masked-placebo controlled clinical trial, 31 eyes of 31 patients were randomly assigned into two groups. only patients with history of ophthalmic or head trauma within the past 7 days were included. unconscious patients, th...

3000 patients, having undergone fiber - optic bronchoscopy (foli) over 10 years, in our hospital were evaluated. thec aim of this study was to determine the prevalence of lung cancer in iran and their correlation with somking and to study the clinical anil radiological signs in different cancers ami the role of fiber-optic bronchoscopy in their diagnosis and the hazards of this method, 'llxe co...

the purpose of this study was to investigate magnetic resonance imaging (mri) of the normal feline eyeand optic nerves using t1-weighted and t2-weighted images. a total of 6 healthy female domestic short haircats age 2-2.5 years and weighing 3.2 ± 0.4 kg were selected. magnetic resonance imaging data werecollected using gemsow (philips) at a magnetic field strength of 1.5 t. dorsal, sagittal, a...

PURPOSE To evaluate the radiation dose-volume effects of optic nerves and chiasm by visual psychophysical, electrophysiologic tests, and optical coherence tomography in patients with locally advanced nasopharyngeal carcinoma. MATERIALS AND METHODS A series of visual tests including visual acuity, visual field, contrast sensitivity, visual evoked potential, and optical coherence tomography wer...

We made intracellular recordings from 74 neurons in the optic layer of the rat superior colliculus (SC). Resting membrane potentials were -62.3 +/- 6.2 (SD) mV, and input resistances were 37.9 +/- 10.1 MOmega. Optic layer neurons had large sodium spikes (74.2 +/- 12.3 mV) with an overshoot of 12 mV and a half-amplitude duration of 0.75 +/- 0.2 ms. Each sodium spike was followed by two afterhype...

Stem cells are undifferentiated cells that have the ability to convert to different types of cells and after dividing, they can produce their own cells or other cells. Axons of the retinal ganglion cells, from the optic nerve. These cells lose the ability to regenerate themselves before birth. Optic nerve degeneration can result from various causes including increased intraocular pressure, comp...

Optic neuritis and myelitis are manifestations in both multiple sclerosis (MS) and neuromyelitis optica (NMO). But unlike MS, NMO is characterized by severe optic neuritis, longitudinally extensive and transverse myelitis, and the presence of aquaporin-4 antibody. Since patients with optic neuritis and myelitis have often been diagnosed with "optic-spinal MS (OSMS)" in Asia, it was obscure whet...