نتایج جستجو برای: opiate system

تعداد نتایج: 2234993  

2017
Purvi Purohit Naresh Nebhinani Praveen Sharma

BACKGROUND There is a paucity of data on frequency of metabolic syndrome (MS), insulin resistance (IR), and oxidative stress in Indian opiate users without comorbidities. OBJECTIVES To determine the influence of opiate use on frequency of MS, homeostasis model assessment for IR (HOMA-IR), high-sensitivity C-reactive protein (hs-CRP), and oxidative stress in opiate-dependent male patients with...

ژورنال: اعتیاد پژوهی 2012
سلیمانیان, علی‌اکبر , فیروزآبادی, عباس ,

Introduction: This study was carried out with the aim of evaluating the relationship between motivational structure, mental health and attitude to opiate substances in a sample of North-Khorasan's university students. Method: In a descriptive cross-sectional study, 400 participants (200 males and 200 females) were selected by stratified random sampling of three universities of north khorasan. A...

Journal: :Bulletin of the World Health Organization 2013
Ruth Birgin

2008
Colin Drummond Katherine Perryman

BACKGROUND: Several pharmacological approaches are effective in the treatment

2013
Shervin Gholizadeh Ninglei Sun Xavier De Jaeger Melanie Bechard Lique Coolen Steven R. Laviolette

The consolidation of newly acquired memories involves the temporal transition from a recent, less stable trace to a more permanent consolidated form. Opiates possess potent rewarding effects and produce powerful associative memories. The activation of these memories is associated with opiate abuse relapse phenomena and the persistence of compulsive opiate dependence. However, the neuronal, mole...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1977
S K Sharma W A Klee M Nirenberg

Reactions mediated by the opiate receptors that inhibit adenylate cyclase (EC 4.6.1.1) are closely coupled to subsequent reactions that gradually increase adenylate cyclase activity of neuroblastoma X glioma NG108-15 hybrid cells. Opiate-treated cells have higher basal-, prostaglandin E1-, and 2-chloroadenosine-stimulated activities than do control cells. However, NaF or guanosine 5'-(beta, gam...

Journal: :روانشناسی تحولی 0
فاطمه دهقانی آرانی دانشجوی دکترا دانشگاه تهران رضا رستمی استادیار دانشگاه تهران عباس رحمان نژاد استادیار دانشگاه تهران

the efficacy of neurofeedback treatment on psychopathological symptoms in addicted male patients was assessed. participants were 20 opiate dependent patients who was seeking medication treatment. after completing the symptom chekclist-90-revised (derogatis, 1975), participants were randomly assigned to an experimental or a witness group. the experimental group received 30 sessions of neurofeedb...

Journal: :The Journal of clinical investigation 2007
Gavril W Pasternak

Repeated use of opiate analgesic drugs such as morphine for the relief of chronic pain may result in the development of opiate tolerance and dependence, leading to a narrowing of the drug's therapeutic index and increased side effects. Previous preclinical work has shown that interruption of a signaling cascade involving the N-methyl-D-aspartate receptor and NO prevents morphine tolerance. In t...

Journal: :Irish journal of medical science 2001
M Ward J Barry

BACKGROUND Intravenous drug misuse, principally heroin, occurs primarily in the Greater Dublin area. Methadone maintenance treatment has been an important part of the response to opiate misuse in Dublin since 1992. AIMS To determine the number of opiate-related deaths in Dublin City and County during 1999, to establish the number of methadone-related deaths and determine the proportion of dea...

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