conclusions the obtained results showed that hcv infection was an alarming problem among opiate users in the eastern part of turkey. it is suggested to rapidly diagnose the infected persons; thus preventive measures and appropriate control may limit further transmission of these infections. background hepatitis b, hepatitis c and hiv infections constitute serious healthcare problems worldwide. ...

The aim of the present study was to evaluate, two different doses of sublingual buprenorphine (2 mg and 4 mg) among patients on maintenance treatment and to assess the relationship of steady state plasma level with craving. Twenty three male opioid dependent (ICD-10 DCR) subjects, were assigned to double blind randomized controlled trial of 2 and 4 mg/day doses of buprenorphine in an inpatient ...

OBJECTIVE To evaluate the economic impact of buprenorphine/naloxone (B/N) as an agonist opioid treatment for opiate dependence. METHODS A budgetary impact analysis model was designed to calculate the annual costs (drugs and associated costs) to the Spanish National Healthcare System of methadone versus B/N. Data for the model were obtained from official databases and expert panel opinion. R...

This study was undertaken to evaluate the reasons for lapse, relapse and the coping behaviors in a group of recently abstinent subjects with opioid dependence. Retrospective qualitative and quantitative evaluation of the reasons for lapse, relapse and coping behaviors were done using structured questionnaires and semi-structured interviews. Eighty-four subjects from inpatient and outpatient set...

BACKGROUND Substance misuse is associated with cognitive dysfunction. We used a stop signal task to examine deficits in cognitive control in individuals with opioid dependence (OD). We examined how response inhibition and post-error slowing are compromised and whether methadone maintenance treatment (MMT), abstinence duration, and psychiatric comorbidity are related to these measures in individ...

INTRODUCTION Studies have reported that females who drop out prematurely from inpatient treatment have poor treatment outcome. However, literature from India is limited in this regard. METHODS We reviewed case records of female patients admitted with opioid use disorder at NDDTC, Ghaziabad between January 1, 2008 and December 31, 2012 to study the predictors of inpatient treatment completion ...

Despite decades of experience treating heroin or prescription opioid dependence with methadone or buprenorphine--two forms of opioid substitution therapy--gaps remain between current practices and evidence-based standards in both Canada and the United States. This is largely because of regulatory constraints and pervasive suboptimal clinical practices. Fewer than 10 percent of all people depend...

BACKGROUND Opioid dependence (OD) is a chronic, relapsing condition representing a significant societal burden in Asia. Opioid maintenance treatment (OMT) in combination with psychosocial treatment is considered to be the most effective strategy to treat opioid dependence. In Malaysia, about 52,000 patients reported receiving OMT in December 2012. OBJECTIVE The International Survey Informing ...

Objective: This preliminary study was conducted to establish the minimal counseling requirements for buprenorphine maintenance in primary care settings. A brief, nurse-administered, medically focused counseling approach for buprenorphinemaintained patients, Medical Management (MM), was designed by the authors. To evaluate preliminary feasibility and efficacy of MM prior to using it in a primary...

Detoxification, the initial step in the treatment of opiate dependence (Freedman, 1980) has been facing difficulties in our country as the widely used drug methadone is not available. Earlier practices were either abrupt withdrawal or gradual tapering of the dose of the opiate to which the individual was dependent. Recently clonidine has been used with success for detoxification and treatment o...