Background EC-IC bypass surgery is performed in the patients with internal carotid artery occlusion (ICO) or who undergo ligature of the internal carotid artery (ICA) for the treatment of aneurysm. The flow directions are varied according to the relative pressure of some intracranial arteries following post EC-IC bypass. Abnormal retrograde flow is often observed at the ipsilateral M1 segment o...

OBJECTIVE To report real-time ophthalmoscopic findings during superselective intraophthalmic artery chemotherapy (SSIOAC) in a nonhuman primate model. METHODS Six adult male Rhesus macaques (Macacca mulatta) were randomly assigned to 1 of 2 treatment cohorts: melphalan (5 mg/30 mL) or carboplatin (30 mg/30 mL). Each animal underwent 3 separate SSIOAC procedures at 3-week intervals. Digital re...