Prognostic modelling involves grouping patients by risk of adverse outcome, typically by stratifying a severity of illness index obtained from a classifier or survival model. The assignment of thresholds on the risk index depends of pairwise statistical significance tests, notably the log-rank test. This paper proposes a new methodology to substantially improve the robustness of the stratificat...

Process safety might be considered as the most important area to improve several aspects in the process industry design. Ways of dealing with hazards include means to either control them or totally remove them. Both control and removal ways can be applied during the design stage to produce inherently safer designs. There exist several practical examples where issues related to inherently safer ...

This article introduces the subject of terrorism and counter-terrorism by means of a two-person bimatrix game that provides some insight into the behaviour of the two players. We then examine three important areas in counter-terrorism tasks: the detection of terrorist cells and how to render them inoperable, the fortification of assets in order to protect them from terrorist attacks and the opt...

A stainless steel, six-inch valve capable of closing in apprcximately 10 milliseconds has been developed at the Stanford Linear Accelerator Center. The valve will be automatically and zemotely operable, allowing it to be used in the S:dC be:nl switchyard area where high radi,tion levels wil:. prohi,it personnel pccess. The 7roblLdns of '.rigge-ing mechanical release, Lalve gute acceleratior and...

Software fault tree analysis (SFTA) [1] is widely used for analyzing software requiring high-reliability. In SFTA, experts predict failures of system through HAZOP (Hazard and Operability study) or FMEA (Failure Mode and Effects Analysis) and draw software fault trees about the failures. Quality and cost of the software fault tree, therefore, depend on knowledge and experience of the experts. T...

The paper introduce a concept analysis method based on ontology, and applied to the construction of military knowledge. Using the method we establish an ontological structure and concept between the military knowledge and communication, in order to eliminate differences between military knowledge. The conceptual analysis of knowledge can be constructed to the knowledge operability can be realiz...

Primary/Lead Author David Bogle (editor); Engell; Ross & Pistikopoulos; Binder, Abel & Marquardt; Petersen, Jorgensen & Skogestad; Mathison; Backx, Bosgra & Marquardt; Hovd & Skogestad. Identification TWG3/D Bogle/R&D SoA Review/Rev P/1998-01-12 Purpose Discussion paper providing an overview of the state of the art in Research into the various aspects of Flexibility, Operability & Dynamics iden...

A widely used hazard identification technique within the process industry is HAZOP (hazard and operability study). To overcome the repetitive and time-consuming nature of the technique automated systems are being developed. This work considers batch processes, in which material undergoes processing in distinct stages within the plant equipment items according to a set of operating procedures, r...