Sperm maturation in the epididymis may involve differences between mature and immature spermatozoa in their volume regulatory osmolyte response. Spermatozoa obtained from the rat caput and cauda epididymidis were examined for their ability to regulate volume after transfer from in situ epididymal osmolality (measured to be 343 +/- 13 and 365 +/- 19 mmol kg(-1), respectively) to that of the fema...

Studies on the distribution of Na+, K+-dependent, Mg2+ dependent and Ca2+ dependent Adenosine Triphosphatase (ATP-ases) in the testes, epididymis, seminal vesicles and prostate glands of mature bonnet monkeys were carried out with and without Testosterone propionate (TP) treatment. Comparatively, the Ca2+ dependent ATP-ase was very active in the testes, caput and cauda epididymis and prostate o...

Hamster spermatozoa were isolated from the caput, corpus and cauda epididymidis. They were observed in culture medium at 37 degrees C with a phase-contrast microscope and their motility recorded cinematographically. About 20 p. 100 of the caput epididymidis spermatozoa were motile and moved in a confined space with no forward progression. 30 p. 100 of the corpus epididymidis spermatozoa were mo...

Sperm cell surface proteins and proteins of their surrounding fluids are reported to be proteolytically processed in relation to acquisition of sperm fertility during epididymal transit. Several of these proteins might be potential targets for subtilisin-like pro-protein convertase. Using immunochemistry and mass spectrometry analysis, we found that an 80 kDa form of furin (EC 3.4.21.75) is pre...

Behavioral changes resembling human athetoid and choreiform hyperkinesias were produced b y unilateral injections of L-3,4-dihydroxyphenylalanine (l-D O P A ), dopamine, 3-m ethoxy-tyram ine and dexamphetamine into the rostromedial part of the caput caudati o f ca ts; saline, noradrenaline and 3,4 -dihydroxyphenylacetio acid were ineffective. Pretreatment with the tyrosine hydroxylase inhibitor...

Behavioral changes resembling human athetoid and choreiform hyperkinesias were produced b y unilateral injections of L-3,4-dihydroxyphenylalanine (l-D O P A ), dopamine, 3-m ethoxy-tyram ine and dexamphetamine into the rostromedial part of the caput caudati o f ca ts; saline, noradrenaline and 3,4 -dihydroxyphenylacetio acid were ineffective. Pretreatment with the tyrosine hydroxylase inhibitor...