Recently, a model was proposed to assess hepatic insulin sensitivity during a meal, i.e., the ability of insulin to suppress glucose production (EGP), SI (P). The model was developed on EGP data obtained from a triple-tracer meal and the tracer-to-tracee clamp technique and validated against the euglycemic hyperinsulinemic clamp. The aim of this study was to assess whether SI (P) can be obtaine...

The paper presents an approach for the on-line monitoring and diagnosis of multi-robot systems where services are provided by a team of robots and the environment is only partially observable via a net of fixed sensors. This kind of systems exhibits complex dynamics where weakly predictable interactions among robots may occur. To face this problem, a model-based approach is adopted: in particul...

Measuring insulin sensitivity during the physiological milieu of oral glucose perturbation, e.g., a meal or an oral glucose tolerance test, would be extremely valuable but difficult since the rate of appearance of absorbed glucose is unknown. The reference method is a tracer two-step one: first, the rate of appearance of glucose (R(a meal)(ref)) is reconstructed by employing the tracer-to-trace...

The mitochondrion has evolved as an important organelle in determining cell survival and cell death. It is involved in a plethora of processes in mammalian cells including ATP production, steroid synthesis, and cell division and cell death. Indeed, mitochondrial dysfunction is associated with numerous human maladies including heart disease. Mitochondrial diseases have traditionally been attribu...

Two types of sabkhas are distinguished in the study coastal area; first type was developed at mouths wadis where sea water enters through high tides; these include; Omm El-Shawesh, Wadi Al-Ain sabkha and Rizk sabkha. A generalized hydrodynamic model for formation this constructed. The second is stretching behind dunes, divided into a longitudinal strip from east to west saline crusts appear som...

The JAVA/A approach aims at semantically well-founded and coherent modelling and programming concepts for components: based on sound theoretical foundations it enhances the widely used UML 2.0 component model by modular analysis and verification techniques and a Java-based architectural programming language. Our JAVA/A component model is inspired by ideas from “Real-Time Object Oriented Modelin...

Abstract The Tramelan-2 borehole (Canton Bern, Switzerland) continuously cored a 275.60 m sequence of Palaeogene to Neogene sediments, providing rare opportunity for sedimentological analysis the Jura Molasse. Lithostratigraphy, sedimentary facies and heavy minerals allow correlation with classical Swiss Evidence clastic input from Alpine non-Alpine sources is consistent deposition at northern ...