Adenomatoid odontogenic tumor is a non-aggressive slow growing epithelial odontogenic tumor with varied clinical and microscopic features. This neoplasm rarely appears as a completely cystic lesion histopathologically; therefore, oral pathologists should be aware of the various histopathologic types of this lesion. The main objective of this case report is to present a rare challenging case o...

Background & Objectives: Odontogenic cysts are among the most frequent destructive lesions of jaws which their pathogenesis and growth mechanism are not cleared. With respect to different roles of mast cells, they may play a role in the pathogenesis and growth of odontogenic cysts. The aim of present study was to evaluate mast cells in the most common odontogenic cyst. Methods:</e...

p53 and PCNA expression in keratocystic odontogenic tumors compared with selected odontogenic cysts Summary: The aim of this study was to evaluate p53 and PCNA expression in different odontogenic lesions regarding their different clinical behaviors. Slices prepared from 94 paraffin-embedded tissue blocks (25 radicular cysts (RC), 23 dentigerous cysts (DC), 23 keratocystic odontogenic tumors (KC...

Adenomatoid odontogenic tumor (AOT), constituting approximately 3-7% of all odontogenic tumors is described as a rare benign epithelial tumor of odontogenic origin. It is composed of odontogenic epithelium arranged in a variety of histoarchitectural presentations and closely resembles an ameloblastoma. AOT is mostly asymptomatic and is usually associated with impacted teeth in maxillary anterio...

he adenomatoid odontogenic tumor (AOT) is a clinically benign lesion. Discussions about the AOT hamartomatous or neoplastic nature, and the probable odontogenic epithelial cell it originates from still exist. This research aimed to study and discuss the subject by the immunohistochemical detection of cytokeratins, laminin, collagen IV, PCNA and p53 in 8 tumor samples and 8 dental follicle sampl...

AIMS AND BACKGROUND The aim of the study was to examine the immunohistochemical expression of a cell-cycle-related factor (p16) in order to elucidate its role in the growth and diffusion of odontogenic tumors. STUDY DESIGN Thirty-six odontogenic tumors were divided into two groups according to their clinical behavior: group A and group B composed of tumors at low and high risk of recurrences,...

BACKGROUND: Odontogenic myxoma (OM) is a locally aggressive neoplasm whose clinicopathological characteristics have not been extensively reported in Nigerians. OBJECTIVE: To describe the clinicopathological characteristics of cases of OM seen at the Lagos University Teaching Hospital in Nigeria. METHODS: A review of both clinical and histopathological records of sixty-three cases of OM diagnose...

Odontogenic tumor is one of the tumors of great significance in the oral region. The process of its development remains obscure. It seems very advantageous in the investigation of dontogenic tumor to establish experimental models in laboratory animals. However, experimental attempts of induction of odontogenic tumor have not been very successful. In recent years, the carcinogenic property of ni...

OBJECTIVES To determine the relative incidence of odontogenic cysts and to identify the main clinicopathological features among patients treated in the Oral Surgery Department of the Dental Clinic of the University of Barcelona (Spain). STUDY DESIGN A retrospective observational study was made of 418 odontogenic cysts diagnosed in 380 patients included in the database of 1235 histopathologica...

INTRODUCTION Odontogenic cutaneous sinus tracts are often misdiagnosed as lesions of non-odontogenic origin, leading to the treatment of patients with unnecessary and ineffective therapies. Sinus tracts of endodontic origin usually respond well to endodontic therapy. However, root canal treatment of mandibular molars with aberrant canal anatomy can be diagnostically and technically challenging....