BACKGROUND Increased serum levels of angiotensin converting enzyme and lysozyme are considered as inflammatory markers for diagnosis of sarcoidosis which is an autoimmune inflammatory disease. The purpose of this study is to evaluate the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and...

BACKGROUND Stevens-Johnson syndrome is often associated with blinding ocular surface cicatricial sequelae. Recent reports have described markedly improved clinical outcomes with the application of amniotic membrane to the ocular surface during the acute phase. Here we describe the clinical outcome of a patient with acute Stevens-Johnson syndrome and severe ocular surface involvement in whom the...

BACKGROUND Lyme arthritis is the most frequent late manifestation of Lyme borreliosis and has been associated with ocular inflammation. METHODS A group of 153 children and adolescents with arthritis, 84 of whom had Lyme arthritis and 69 other causes of arthritis, were followed prospectively for 22-73 (median 44) months in the course of a national study. RESULTS Three of 84 patients with Lym...

Solitary metastasis of uveal melanoma to bone is extremely rare and usually associated with other organ involvement. We present a rare case of an ocular melanoma patient presenting with solitary metastasis to the clavicle two years after enucleation, without any other organ involvement. In this report, we tried to present our treatment strategy for the solitary metastasis of bone.

Introduction Localized Scleroderma (LS) has been associated with central and peripheral nervous system involvement. Facial palsy, extra-ocular movement disorders, trigeminal neuralgia and hemi-masticatory spams are described as primary neurologic involvement. Romberg hypothesized that sympathetic regulation has pathogenic relevance in facial hemiatrophy, which was reproduced experimentally by s...

PURPOSE To identify the frequency of ocular changes in patients with Hansen's disease, living in a colony hospital; to confirm the predilection for the anterior segment of the eye instead of the posterior segment. METHODS Transversal study of 115 eyes of 58 in-patients at João Paulo II colony, Marituba-Pará, from August to October 1999. The epidemiologic data of this research were obtained fr...

PURPOSE The aim of this research is to study the patterns of ocular involvement in patients with biopsy-proven lung sarcoidosis and estimate the level of patients' awareness of possible ocular complications of sarcoidosis. METHODS Fifty patients with biopsy-proven lung sarcoidosis were referred from the Department of Respiratory Medicine, University Hospital of Larissa, Greece. RESULTS The ...