Tacrolimus (TAC) suspension is used to treat moderate severe atopic keratoconjunctivitis (AKC) and vernal (VKC). The objectives of this study were formulate the hydrophobic compound TAC in an aqueous eye drop formulation its ocular biodistribution on topical application a healthy rabbit model, with overall aim using AKC VKC. A thin-film hydration method was encapsulate within chitosan-based amp...