Methods Computation of FFR from CCTA data was performed on 159 vessels in 103 patients undergoing CCTA, invasive coronary angiography, and FFR. Independent core laboratories determined FFRCT and CAD stenosis severity by CCTA. Ischemia was defined by an FFRCT and FFR 0.80, and anatomically obstructive CAD was defined as a CCTA with stenosis 50%. Diagnostic performance of FFRCT and CCTA stenosis ...

INTRODUCTION The association of chest pain versus dyspnea with demographics, coronary angiographic findings, and outcomes of patients undergoing coronary angiography is unknown. MATERIAL AND METHODS We studied 1,053 patients who had coronary angiography to investigate the association of chest pain versus dyspnea with demographics, coronary angiographic findings, and outcomes. RESULTS Of 1,0...

BACKGROUND Women with signs and symptoms of ischemia, no obstructive coronary artery disease (CAD) and preserved left ventricular ejection fraction (EF) often have diastolic dysfunction and experience elevated rates of major adverse cardiac events (MACE), including heart failure (HF) hospitalization with preserved ejection fraction (HFpEF). We evaluated the predictive value of inflammatory biom...

Objectives: This study attempts to determine the silent coronary artery disease (CAD) in a sample of Iraqi Kurdish patients diagnosed with rheumatoid arthritis (RA).
 Methods: A total 50 such from Duhok, Kurdistan region Iraq, underwent multi slices computed tomography (MSCT) angiography 64 calcium (CAC) scores and stenoses.
 Results: 62% cases had score > zero on non-contrast MSCT...

Longitudinal strain (LS) measurements by Speckle Tracking Echocardiography (STE) is a point of care imaging modality that had been documented to have role in NSTEMI/STEMI and stable Coronary artery disease (CAD). This study aims determine the accuracy LS parameters diagnosis predicting severity CAD unstable angina patients with no regional wall motion abnormalities. It was prospective analytica...

Abstract Background The 2021 Guideline for the Evaluation of Chest Pain supports use coronary artery calcium (CAC) score as a reasonable first-line test to identify patients with low likelihood obstructive disease (CAD) who may not require additional testing (class IIa, LOE B). However, recent study from large cohort Northern European raised concerns about added diagnostic value CAC=0 in younge...

BACKGROUND The heme oxygenase-1 gene (HMOX1) promoter polymorphisms modulate its transcription in response to oxidative stress. This study screened for HMOX1 polymorphisms and investigated the association between HMOX1 polymorphisms and coronary artery disease (CAD) in the Korean population. METHODS The study population consisted of patients with CAD with obstructive lesions (n=110), CAD with...

Coronary artery disease (CAD) is one of the leading causes of mortality in chronic obstructive pulmonary disease (COPD). Right ventricular hypertrophy and ischemia are known to occur in COPD due to secondary pulmonary hypertension, but there is a significant link between COPD & CAD, regarding etiology, pathophysiology and precipitating factors. There is a definite role of smoking, respiratory m...