Abstract: The aetiology of hollow visceral myopathy remains poorly understood despite the review histology and is often misdiagnosed. It characterized by impaired intestinal function motility in absence mechanical obstruction, which may be familial (transmitted a dominant or recessive gene) sporadic. Familial rare hereditary myopathic degeneration both gastrointestinal (and urinary tracts) that...

superior vena cava (svc) syndrome is not an uncommon occurrence in patients with malignancy and it is often described as a medical emergency. in majority of the cases, svc syndrome occurs due to mechanical obstruction of the svc by extraluminal compression with primary intrathoracic malignancies. however, intraluminal obstruction due to thrombosis can also produce symptoms and signs of svc synd...

Chronic intestinal pseudo-obstruction (CIPO) is a rare gastrointestinal motility disorder that presents with symptoms, physical exam, and imaging findings of mechanical bowel obstruction without an anatomical obstruction. Multiple etiologies, including enteric or extrinsic neuropathic dysfunction, myopathic dysfunction the interstitial cells Cajal, cause CIPO’s pathogenesis. The presentation CI...

Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...

Gastrointestinal motility and plasma PYY levels were investigated under chronic progressive large bowel obstruction in dogs. The obstruction device was applied around the descending colon at a laparotomy and gastrointestinal motility was recorded with strain gauge force transducers in the conscious state. Complete obstruction occurred at 26 days (21-33 days). The duration of postprandial interr...

Ureteral obstruction can occur due to various pathologies. Ureteral calculus is one of the commonest causes. Extra luminal and less commonly intra luminal Ureteral obstruction can occur due to malignancy. Unrecognised Ischemic injuries during gynaecological surgery can cause ureteric stricture and obstruction at a later date. Traumatic injuries have also been documented as an important cause of...

Intestinal obstruction is a common complication in patients with advanced abdominal or pelvic cancer. The synthetic somatostatin analogue octreotide can help relieve nausea, vomiting and pain in patients with inoperable obstruction. Here, we report a case of recurrent intestinal obstruction in a patient with adenocarcinoma. Although the obstruction was resolved after 3 days of treatment with oc...

Colonic pseudo-obstruction is a condition of distention of colon with signs and symptoms of colonic obstruction in the absence of an actual mechanical cause of obstruction. It is a poorly understood disease that is characterized by functional large bowel obstruction. Intestinal pseudo-obstruction was described in 1938 by the German surgeon W. Weiss who reported mega-duodenum in 6 persons in 3 g...

Congenital duodenal obstruction is usually characterized by onset of early vomiting due to high bowel obstruction. Presentation of congenital duodenal obstruction with acute gastrointestinal bleeding is very uncommon. We present an unusual case of congenital intrinsic duodenal obstruction associated with the Down's syndrome presenting with hematemesis secondary to duodenitis. This is a rare pre...

Chronic intestinal pseudo-obstruction is a known complication of patients with systemic sclerosis, manifested as nausea, vomiting, constipation, abdominal distension and pain. We report a series of cases with systemic sclerosis that presented with signs of intestinal obstruction. In all cases, the differentiation between a pseudo-obstruction and true mechanical obstruction remained a formidable...