نتایج جستجو برای: nuclear respiratory factor1
تعداد نتایج: 442247 فیلتر نتایج به سال:
Pulmonary arterial hypertension (PAH) is a fatal disease associated with inflammation and pathological remodeling of the pulmonary artery (PA). Interleukin (IL)-10 is a pleiotropic antiinflammatory cytokine with vasculoprotective properties. Here, we report the preventive effects of IL-10 on monocrotaline-induced PAH. Three-week-old Wistar rats were intramuscularly injected with an adeno-associ...
background: the earlier atomic bomb explosion in hiroshima and nagasaki, and three worth mentioning nuclear accidents - detonation at fukushima daiichi nuclear plant, chernobyl nuclear fallout and an accident at three mile island nuclear power plant have made us more worried about the secure exploitation of nuclear energy. the central focus of this paper is to review radiation-mediated health e...
We have studied the dynamics of mitochondrial DNA maintenance and segregation in human cells using serial cybrid transfer of partially duplicated mitochondrial DNA, from a mitochondrial myopathy patient, to two distinct recipient cell types. The results indicate two radically different outcomes dependent upon nuclear background. In one case (lung carcinoma) there is systematic loss of the parti...
Mitochondrial complex I, the largest component of the mitochondrial respiratory chain, comprises 44 subunits of which 7 are encoded by the mitochondrial genome and the remainder by the nuclear genome. Isolated complex I deficiencies represent a major contribution within the group of respiratory chain defects. We report an atypical case carrying a homozygous NDUFS4 missense mutation, with late-o...
Oxidative phosphorylation requires assembly of the protein products of both mitochondrial and of nuclear genomes into functional respiratory complexes. Cellular respiration can be compromised when mitochondrial DNA (mtDNA) sequences are corrupted. Oxidative damage resulting from reactive oxygen species (ROS) produced during respiration is probably a major source of mitochondrial genomic instabi...
The Danish Lung Cancer Screening Trial John Brodersen, Haseem Ashraf, Karen Bach, Paul Clementsen, Asger Dirksen, Martin Døssing, Peter Gøtzsche, Hanne Hansen, Jann Mortensen, Jesper H. Pedersen, Birgit Guldhammer Skov, Klaus Richter, Niels Seersholm, Hanne Thorsen Department of General Practice, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark; Departments of Respirato...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید