The major obstacle is leukemia relapse for refractory leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). We previously introduced a strategy of sequential intensified conditioning and early rapid immunosupressant withdrawal for refractory leukemia undergoing allo-HSCT, with 5-year overall survival (OS) and 3-year relapse rate of 44.6% and 33.3%. To reduce leukem...

The study was designed to examine the effect of persistent temporomandibular joint (TMJ) inflammation on neuronal activation in the descending pain modulatory system in response to noxious stimulus. Formalin was injected into the left masseter muscle or hindpaw of rats 10 days after injection of the left TMJ with saline or complete Freund's adjuvant (CFA). The results showed that 10-day persist...

Due to the increasing growth of Web Services, Quality of Service (QoS) is becoming a key issue in web services community. Providers and clients need to use QoS-aware architectures to get/ensure end-to-end QoS. The QoS delivery to clients is highly affected by the web service performance itself, by the hosting platform (e.g., Application Server) and by the underlying network (e.g., Internet). Th...

The utility of routine chimerism analysis as a prognostic indicator of subsequent outcomes after allogeneic hematopoietic cell transplantation (HCT) with myeloablative conditioning regimens remains controversial. To address this controversy, routine chimerism test results at 2 to 6 months after HCT with myeloablative conditioning regimens were evaluated for association with subsequent risk of c...

BACKGROUND Affections are thought to regulate pain perception through the descending pain inhibitory system in the central nervous system. In this study, we examined in mice the affective change by inhalation of the lemon oil, which is well used for aromatherapy, and the effect of lemon odor on pain sensation. We also examined the anterior cingulate cortex (ACC) and descending pain inhibitory s...

Religion is an influential and resilient phenomenon that parades no cryptograms of decline. It incites the deepest obligation, emotion, sharp action, strong dialogues study for practitioners, opponents fence-sitters. Any anthropoid who familiar with world around them understands religion a powerful probing demands better understanding through inquiries. Despite force religion, 21st century has ...

Natural resource management (NRM) is conducted within a complex context. This particularly true at the interface of public and private interests where policy actions are often closely scrutinized by stakeholders. In these settings, natural managers seek to achieve multiple objectives including ecosystem restoration, biodiversity conservation, commodity production, provision recreation opportuni...

Microbialites–layered, organosedimentary deposits–exist in the geologic record and extend back deep time, including all estimated times of inner core nucleation. Microbialites may preserve magnetic field variations at high-resolution based on their growth rates. Previous studies have shown that microbialites can a stable magnetization. However, timing origin microbialite magnetization were not ...