BACKGROUND The prevalence of Methicillin resistant Staphylococcus aureus (MRSA) is progressively increasing globally with significant regional variation. Understanding the Staphylococcus aureus lineages is crucial in controlling nosocomial infections. Recent studies on S. aureus in Uganda have revealed an escalating burden of MRSA. However, the S. aureus genotypes circulating among patients are...

In 928 Dallas County Jail detainees, nasal carriage of Staphylococcus aureus was found in 32.8% (26.5% methicillin-susceptible Staphylococcus aureus [MSSA] and 6.3% methicillin-resistant S. aureus [MRSA]), and hand carriage was found in 24.9% (20.7% MSSA and 4.1% MRSA). Among MRSA nasal carriers, 41% had hand MRSA carriage; 29% with hand MRSA carriage had no nasal S. aureus carriage. The preval...

Methicillin-resistant Staphylococcus aureus sequence type 398 (ST398 MRSA) was identified in Dutch pigs and pig farmers. ST398 methicillin-susceptible S. aureus circulates among humans at low frequency (0.2%) but was isolated in 3 human cases of bacteremia (2.1%; p = 0.026). Although its natural host is probably porcine, ST398 MRSA likely causes infections in humans.

The pathogen has been found to cause a plethora of diseases such as blood stream infections, skin and soft tissue infections, pneumonia and hospital acquired postoperative wound infections [2]. Though the diseases are treatable by the usage of antibiotics, emergence of multi drug resistant strains have been reported worldwide, thereby complicating the treatment of infections caused by Staphyloc...

Affi liations: From the Division of Clinical Science, St. George’s University of London. Financial/nonfi nancial disclosures: The author has reported to CHEST the following confl icts of interest: Dr Jones has received consulting fees and speakers honoraria from GlaxoSmithKline. Correspondence to: Paul W. Jones, PhD, Division of Clinical Science, St. George’s University of London, Cranmer Terr,...

INTRODUCTION Propofol and Ephedrine are commonly used during anesthesia maintenance, the former as a hypnotic agent and the later as a vasopressor. The addition of propofol to ephedrine or administration of ephedrine before propofol injection is useful for decreasing or preventing propofol related hemodynamic changes and vascular pain. This in vitro study evaluated the antibacterial effect on c...

background: tourniquets used repeatedly on patients for blood sampling are a potential source of nosocomial infections. they harbor numerous microorganisms, including methicillin‑resistant staphylococcus aureus (mrsa). the aim of this study was to investigate tourniquets for the presence of microorganisms and to ascertain the infection control practices of health care workers. methods: a cross‑...

Staphylococcus aureus has the ability to asymptomatically colonize the normal population either persistently or transiently. 30% of humans are likely to be nasal carriers. Person to person contact or contact with fomites plays a role in its transmission. Loss of normal skin barrier and presence of predisposing factors such as diabetes and HIV complicates infection. Staphylococcus aureus causes ...

We studied the transmissibility of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and healthcare-associated methicillin-resistant S. aureus (HA-MRSA) strains and the association of MRSA colonization pressure and MRSA transmission in critically ill children. Importantly, we found that in hospitalized children MRSA colonization pressure above 10% increases the risk of ...