background:in recent years, the use of chemicals in agriculture, industry, and public health has become so common that the environment is continuously contaminated by the toxic substance-like metals. aluminum released due to anthropogenic activities such as mining and industrial uses. aluminium has several industrial uses. the present study was designed to investigate the effect of aluminium ch...

BACKGROUND Statins can reduce reproductive damage induced by obesity or high-fat diet (HFD), but the specific regulatory mechanisms are largely unknown. Since mTOR/p70s6k sinaling promotes spermatogonia proliferation and spermatogenesis, we hypothesized that this pathway will be involved in the protective effects of statin in HFD-induced reproductive dysfunction. METHODS Male Sprague Dawley r...

The aim of this study was to analyse the multigenerational effects of para-nonylphenol (NP) and resveratrol (RES) on the body weight, organ weight and reproductive fitness of outbred CD-1 mice. The data indicate that in male mice, NP had an effect on the weight of selected reproductive organs and the kidneys in the parental (P) generation males. Effects on selected reproductive organs, the live...

BACKGROUND There is increasing evidence that reproductive abnormalities are increasing in frequency in both human population and among wild fauna. This increase is probably related to exposure to toxic contaminants in the environment. The use of sentinel species to raise alarms relating to human reproductive health has been strongly recommended. However, no simultaneous studies at the same site...

Aspirin (Acetylsalicylic acid) is widely used in human and veterinary as anti-inflammatory, cardiovascular prophylaxis, anti-clotting agent and to decrease cancer risk. However, it is often misor over-consumed, including in population subgroups, such as elite athletes, to prevent pain and treat injuries. Many risks associated with its usage have been reported but there is a deficiency of inform...

hormonally active agents are widespread in the environment and exist in the human diet. there isinsufficient knowledge regarding the influence of phytochemicals on the pathophysiology of the malereproductive system. kiwi is a rich source of phytochemicals such as flavones (with estrogenic activity),serotonin and vitamin c. these components can influence the hormones and interfere with reproduct...

BACKGROUND Currently, relation between reactive oxygen species (ROS) ROS concentration and semen quality was indicated. Saffron has traditionally been not only considered as a food additive but also as a medicinal herb, which has a good antioxidant properties. OBJECTIVE The aim of this study was to evaluate the protection potency of saffron and vitamin E on sperm chromatin integrity. MATERI...

Participation rates in epidemiologic studies on semen quality are generally very low, raising concerns as to the potential for selection bias. Since hormones both initiate and maintain spermatogenesis, they may serve as surrogates of semen quality in epidemiologic studies. For this reason, in the present study, we explored the influence and predictive ability of reproductive and thyroid hormone...

Background: DZN (diazinon) is an organophosphate insecticide that had been used in agriculture and for domestic and veterinary use for several years and caused many negative effects on plants and animal species, especially on human. The aim of present study was to evaluate the effects of DZN on MDA (malondialdehyde) and GSH (glutathione) levels in female rat reproductive tissue (ovary) and to a...