Rotaviruses, segmented double-stranded RNA viruses, co-opt the eukaryotic translation machinery with the aid of nonstructural protein 3 (NSP3), a rotaviral functional homolog of the cellular poly(A) binding protein (PABP). NSP3 binds to viral mRNA 3' consensus sequences and circularizes mRNA via interactions with eIF4G. Here, we present the X-ray structure of the C-terminal domain of NSP3 (NSP3...

the liver is an organ at risk (oar) in radiotherapy of thoracic and abdominal tumors such as gastric, distal esophagus, lower lung and breast, bile duct, pancreas and whole abdomen. in this study the alteration in liver functional tests (lft) of these patients during radiotherapy was investigated. to that end, the level of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), ...

background bovine viral diarrhea (bvd) is an economically important disease of cattle with a worldwide distribution. diagnosis of bvd relies on laboratory-based detections of its viral causing agent or virus specific antibodies. the most common laboratory method used for this purpose is the elisa. bovine viral diarrhea virus (bvdv) nonstructural protein 3 (ns3) is one of the most highly conserv...

This paper examines differences in performances of a range of torsionally stiff and flexible single story buildings designed with the provisions of Iranian Standard 2800. Seismic nonlinear dynamic time history behavior of eight building models subjected to seven horizontal bi-directional design spectra compatible ground motions are investigated. These models cover a wide range of very torsional...

introduction because of expansion of agricultural activities and excessive use of chemical fertilizers and location of municipal and industrial wastewater of andimeshk, it is possible for this aquifer to be polluted. therefore, the aim of present study is to assess the aquifer vulnerability of andimeshk plain and recognition of sensitive areas against pollution which this work can be conducted ...

Pathology and determination of students' moral vulnerability is significant step in their security against cultural, social, value, and moral changes. The present study has been done to assess the students' moral vulnerability. The theoretical framework composed of theories of Durkheim, Englehart and Lerner. By the survey technique, this study has examined the relationship between the moral vul...

this paper examines differences in performances of a range of torsionally stiff and flexible single story buildings designed with the provisions of iranian standard 2800. seismic nonlinear dynamic time history behavior of eight building models subjected to seven horizontal bi-directional design spectra compatible ground motions are investigated. these models cover a wide range of very torsional...