triphosphatase specific activities were decreased in all subcellular fractions during liver growth induced by both ‘toxic’ and ‘non-toxic’ compounds; however, the content of these enzymes in the whole liver did not change. These changes were due to the fact that proteins having no such enzymic activities were synthesized at a relatively higher rate and accumulated in the endoplasmic reticulum. ...

background: due to the increasing pollution of water resources, this study was carried out for evaluation of water quality pollution indices for monitoring of heavy metals (as, zn, pb and cu) contamination in ghahavand plain, hamadan province, western iran during spring and summer 2012. methods: totally, 20 ground water wells were chosen randomly. the samples were filtered (0.45 μm) and maintai...

In 1932 Hamilton and Schwartz (1) described a method for the detection of small amounts of parathyroid hormone, three to five units, in preparations of the hormone and in blood. In 1936 Hamilton and Highman (2) presented certain modifications of this test designed to make the method particularly applicable to the detection of abnormally large amounts of parathyroid hormone in the blood of patie...

Abstract: Peganum harmala L. (Zygophylaceae) has been used in a variety of practical applications in medical science. Our objective in the current study was to determine the effects of the seed extract on Herpes simplex virus type 1 (HSV-1) replication in Vero cells. Different concentrations (100, 500, 571, 667, 800 and 1000 µg/ml) of the extract were examined. Experiments were carried ...

The maximal chemical concentration that causes an acceptably small or no effect in an organism or isolated cells is an often-sought-after value in toxicology. Existing approaches to derive this value have raised several concerns; thus, it is often chosen case-by-case based on personal experience. To overcome this ambiguity, we propose an approach for choosing the non-toxic concentration (NtC) o...

BACKGROUND Exposure to silica gel, a common desiccant, is considered common and non-toxic although data are limited. OBJECTIVES To evaluate the characteristics of silica gel ingestion, and to attempt to estimate the associated health care costs. METHODS We conducted a one year retrospective review of charts of a national poison information center to characterize ingestions of silica gel and...

The maximal chemical concentration that causes an acceptably small or no effect in an organism or isolated cells is an often-sought-after value in toxicology. Existing approaches to derive this value have raised several concerns; thus, it is often chosen case-by-case based on personal experience. To overcome this ambiguity, we propose an approach for choosing the non-toxic concentration (NtC) o...