نتایج جستجو برای: non steroidal

تعداد نتایج: 1318815  

2010
Ashish Kumar Ved Prakash SINGH Raj Kumar Chethampadi Gopi

with steroidal and non-steroidal anti inflammatory drugs (NSAIDs). NSAIDs are drug with analgesic, antipyretic and in higher doses anti inflammatory effects. They inhibit synthesis of inflammation mediators. Most NSAIDs act as non-selective inhibitors of the enzyme cyclooxygenase (COX), by inhibiting the metabolism of arachidonic acid. COX catalyses the formation of prostaglandins (PGs) and thr...

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Journal: :Molecules 2015
Zhishu Tang Guolong Li Jie Yang Jinao Duan Dawei Qian Jianming Guo Zhenhua Zhu Zhongxing Song

A rapid, selective and sensitive UPLC-MS/MS assay was established to determine the plasma concentrations of four steroidal saponins. Sprague-Dawley rats were allocated to four groups which were orally administered Anemarrhena asphodeloides extracts (ASE), ASE combined with macromolecular fraction (ASE-MF), ASE combined with small molecule fraction (ASE-SF) and ASE combined with small molecule a...

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Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2002
Bernadete P da Silva Allyne C de Sousa Graziela M Silva Tatiana P Mendes José P Parente

A new steroidal saponin was isolated from the leaves of Agave attenuata Salm-Dyck. Its structure was established as (3beta,5beta,22alpha,25S)-26-(beta-D-glucopyranosyloxy)-22-methoxyfurostan-3-yl O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside. The structural identification was performed using...

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Journal: :Ensho 1984

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2014
Camilla Fusi Serena Materazzi Silvia Benemei Elisabetta Coppi Gabriela Trevisan Ilaria M. Marone Daiana Minocci Francesco De Logu Tiziano Tuccinardi Maria Rosaria Di Tommaso Tommaso Susini Gloriano Moneti Giuseppe Pieraccini Pierangelo Geppetti Romina Nassini

Use of aromatase inhibitors (AIs), exemestane, letrozole and anastrozole, for breast cancer therapy is associated with severe pain symptoms, the underlying mechanism of which is unknown. The electrophilic nature of AIs suggests that they may target the transient receptor potential ankyrin 1 (TRPA1) channel, a major pathway in pain transmission and neurogenic inflammation. AIs evoke TRPA1-mediat...

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Journal: :Al-Azhar Medical Journal 2020

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Journal: :Journal of the South African Veterinary Association 2001
K E Joubert

According to a survey, non-steroidal anti-inflammatory agents were the most popular analgesic used in South Africa for management of peri-operative pain, acute post-operative pain and chronic pain. The most popular non-steroidal anti-inflammatory agents are flunixin meglumine and phenylbutazone. The most popular opioid type drug is buprenorphine, followed by morphine. In the peri-operative sett...

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Journal: :Hepato-gastroenterology 1985
M J Langman

Non-steroidal anti-inflammatory drugs have been clearly shown to increase the chances of peptic ulcer and its complications. Risk factors associated with this propensity are as yet poorly and inconsistently defined. Clinicians have long accepted that non-steroidal anti-inflammatory drug (NSAID) treatment may cause peptic ulcer and its complications. In assessing the chances it is necessary to d...

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Journal: :British medical journal 1982
S R Heller I W Fellows A L Ogilvie M Atkinson

Drug histories were obtained from 76 patients at the time of initial Eder-Puestow dilatation for benign oesophageal stricture. Six patients had consumed drugs known to cause oesophageal ulceration (emepronium bromide and potassium preparations). Of the remaining 70 patients, 22 had regularly taken a non-steroidal anti-inflammatory drug before the onset of dysphagia compared with 10 patients in ...

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Journal: :Annals of palliative medicine 2021

Background: To explore the clinical efficacy, safety, and prevention of major adverse reactions non-steroidal anti-inflammatory drug celecoxib combined with OxyContin Pregabalin in treatment cancerous pudendal neuralgia.

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