OBJECTIVE The Sardinian type 1 diabetes register represented the basis to determine the most recent trends and the age distribution of type 1 diabetes incidence among Sardinians <15 years of age during 1989-1999. Part of the data (1989-1998) has been already published by the EURODIAB Group with a lower completeness of ascertainment (87%). The geographical distribution of type 1 diabetes risk wa...

OBJECTIVE The burdens imposed on a child and his/her parents by a diagnosis of type 1 diabetes mellitus (T1DM) adversely affect their health-related quality of life (HRQoL). HRQoL is important for prognosis and is related to metabolic control. To evaluate the HRQoL of Turkish children and adolescents with T1DM and to assess the correlation of HRQoL subscales (including physical and psychosocial...

OBJECTIVE To estimate the prevalence rate of depression among adults with diabetes using a large population-based sample in the U.S. RESEARCH DESIGN AND METHODS Data from the 2006 Behavioral Risk Factor Surveillance System, a standardized telephone survey among U.S. adults aged >or=18 years, were analyzed (n = 18,814). The Patient Health Questionnaire diagnostic algorithm was used to identify...

OBJECTIVE Glycosylated hemoglobin (HbA(1c)) recently has been recommended for the diagnosis of diabetes by the American Diabetes Association, but its value in the prediction of type 2 diabetes is poorly understood. In this study we evaluated how high-normal HbA(1c) levels predict type 2 diabetes. RESEARCH DESIGN AND METHODS We measured HbA(1c) in 919 Caucasian subjects, aged 40-79 years, and ...

RESEARCH DESIGN AND METHODS — During 2001–2002, we randomly enrolled 1,514 men (18–87 years old) and 1,528 women (18 – 89 years old) from the Attica region of Greece (of them, 5% of men and 3% of women were excluded because of history of cardiovascular diseases). Diabetes was defined according to the established criteria of the American Diabetes Association (11). Only subjects with type 2 diabe...

OBJECTIVE To examine the relationships among negative attributions of friend and peer reactions to diabetes management in social situations, anticipated adherence difficulties, friend support, diabetes stress, and metabolic control. METHODS A sample of 102 adolescents with Type 1 diabetes completed instruments measuring attribution of friend and peer reactions, anticipated adherence, friend s...

with Hb AIc. Patients with very high Hb Alc values possibly represent a subgroup of the diabetic population, outside the normal criterion oflong-term control, during a phase ofmetabolic decompensation; and they may show features more typical of the lipid disturbances of ketosis than of long-term diabetic control. Thus our main finding is related not to diabetic control but to the type of diabet...

OBJECTIVE There is increasing evidence that prevention programmes for type 2 diabetes mellitus (T2DM) and obesity need to consider individual and regional risk factors. Our objective is to assess the independent association of area level deprivation with T2DM and obesity controlling for individual risk factors in a large study covering the whole of Germany. METHODS We combined data from two c...

BACKGROUND AND OBJECTIVE We decided to assess the geographical variability of the incidence of Type 1 diabetes in Catalonia (Spain) in subjects younger than 30 years at onset during the period 1989-1998. The effect of sex, age at onset, periods of years, and population density was also analyzed. MATERIAL AND METHODS Data were obtained from the prospective Catalan Registry of Diabetes Mellitus...

Diabetes is a severe chronic disease that affects approximately 200 million individuals worldwide, with extremely debilitating effects and considerably high health care costs. The two major classes of diabetes, known as type 1 (previously known as insulin-dependent or juvenile-onset diabetes) and type 2 (non-insulin-dependent diabetes), share common symptoms such as hyperglycemia and the develo...