multiple myeloma (mm), is the second most common blood cancer after non-hodgkin’s lymphoma. genetic changes, structural and numerical chromosome anomalies, are involved in pathogenesis of mm, and are among the most important prognostic factors of disease-associated patient survival. micrornas (mirnas) are small 19-22 nucleotide single-stranded rnas involved in important cellular processes. cyto...

(1) Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood. However, several studies have been conducted to better explain the mechanisms that lead to malignancy; (2) Methods: We reviewed the more recent literature about the pathogenesis of non-melanoma skin cancer focusing on basal cell carcinomas...

Borderline personality disorder is a severe personality disorder for which genetic research has been limited to family studies and classical twin studies. These studies indicate that genetic effects explain 35 to 45% of the variance in borderline personality disorder and borderline personality features. However, effects of non-additive (dominance) genetic factors, non-random mating and cultural...

PURPOSE We developed an absolute risk model to identify individuals in the general population at elevated risk of pancreatic cancer. PATIENTS AND METHODS Using data on 3,349 cases and 3,654 controls from the PanScan Consortium, we developed a relative risk model for men and women of European ancestry based on non-genetic and genetic risk factors for pancreatic cancer. We estimated absolute ri...

In this study, the data was collected on production traits of Murrah buffaloes w.r.t. 1 to 4 parities for period 25 years maintained at Directorate Livestock Farm, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana. The effect non-genetic factors viz; calving, season age first calving parity daily milk yield were found be significant subsequently corrected study comparison vario...