نتایج جستجو برای: nitrobenzylthioinosine nbmpr
تعداد نتایج: 284 فیلتر نتایج به سال:
Pentoxifylline is known to have major effects on cell membrane function in mammalian cells, including human leukocytes. The protective effects of this agent in animal models of infection and inflammation may be due to alterations in phagocyte (neutrophil and macrophage) function. However, the exact mechanism of action of pentoxifylline is unknown. In this study, we evaluated the effect of the d...
Adenosine plays multiple roles in the efficient functioning of the heart by regulating coronary blood flow, cardiac pacemaking, and contractility. Previous studies have implicated the equilibrative nucleoside transporter family member equilibrative nucleoside transporter-1 (ENT1) in the regulation of cardiac adenosine levels. We report here that a second member of this family, ENT4, is also abu...
Although the A1 adenosine receptor (A1 receptor), the main adenosine receptor type in cardiac muscle, is involved in powerful cardioprotective processes such as ischemic preconditioning, the atrial A1 receptor reserve has not yet been quantified for the direct negative inotropic effect of adenosine. In the present study, adenosine concentration-effect (E/c) curves were constructed before and af...
We study deep level defects at the Si/SiO2 interface of 30nm and 5nm SiO2 PMOS devices after negative bias temperature stress (NBTS). Electrical characterization using the direct-current current-voltage (DCIV) technique reveals two defects with different energy levels, recovery and degradation dynamics. To investigate their micro-physical nature, we perform spin dependent recombination (SDR). B...
The work in this paper is focused on designing a NBTI tolerant 6T SRAM cell while maintaining low power operation. We explore the usefulness of switched capacitor circuit to provide NBTI tolerance while reducing overall power consumption. A thorough analysis of the 6T SRAM cell has been done to show the reduction in power consumption of the cell without degrading the read and write stability. T...
We present an overview of negative bias temperature instability ~NBTI! commonly observed in p-channel metal–oxide–semiconductor field-effect transistors when stressed with negative gate voltages at elevated temperatures. We discuss the results of such stress on device and circuit performance and review interface traps and oxide charges, their origin, present understanding, and changes due to NB...
As CMOS technology scaling continues to low nanometers, aging and device wear-out related degradation is a looming concern. With device wear-out mechanisms such as NBTI and PBTI, catalyzed by higher temperature, transistor performance worsens with time. Similarly with electromigration, interconnects become increasingly resistive until they become non-functional. Such phenomena initially manifes...
Katsumi Ohata* Junichi Sato* ABSTRACT: Magnetic shielding for strong magnets using a high-temperature superconductor that can be operated at liquid nitrogen temperature has been studied. Long and large-cross-section (9 mm wide and 0.5 mm thick) 54-filament Bi-2223/Ag tape was developed. Double pancake coils were wound using the tapes having sufficient bending strain tolerance for the react-and-...
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