نتایج جستجو برای: nitric acid 65 merck
تعداد نتایج: 920560 فیلتر نتایج به سال:
Merck & Co., Inc. (Whitehouse Station, NJ), announced that it has successfully completed its $430 million acquisition of Inspire Pharmaceuticals, Inc. (Raleigh, NC). The cash tender offer for all outstanding shares (75.4%) of common stock of Inspire was completed by Monarch Transaction Corp., a wholly owned subsidiary of Merck. The deal, announced in February 2011, allows Merck to expand its op...
Excess activation of glutamate receptors and production of free radicals including nitric oxide may result in severe and irreversible damage to the mammalian central nervous system (CNS), but endogenous defense systems that protect neurons from these insults are poorly understood. Here, we purified and isolated a neuroprotective substance, which has been named "serofendic acid," from a lipophil...
n engl j med 364;19 nejm.org may 12, 2011 1880 the steering committee of an imbalance in cancers. They contacted the DSMBs of IMPROVE-IT and SHARP. Merck was not informed of the imbalance. In July 2008, Merck first became aware of the imbalance after database lock and unblinding and provided that information to the SHARP and IMPROVE-IT steering committees, informing them of the need to notify r...
Abstract Pulping of rice straw was studied using mild nitric acid in conditions. Spent chosen as soil nutrient rather than followed by the liquor recovery. The treated with 11.03% at 90 °C for 3 h, yielded 53.09% pulp. Nitric pulp had high residual lignin and minerals. However, further treatment 7% potassium hydroxide reduced produced kappa number 20.36. papermaking properties KOH showed better...
This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects ...
Nitrous oxide (N2O) is generated as a by-product during the production of adipic acid and nitric acid. The main use for adipic acid is as a component of nylon-6/6; thus production trends are closely correlated with nylon consumption trends. Worldwide, there are very few adipic acid plants. The U.S. is a major producer with three companies in four locations accounting for approximately forty per...
In this case study, DEMO was applied in a real lean six sigma project. The study was conducted in the Merck organisation, a worldwide pharmaceutical company with a research lab and plant for the production of birth control pills in the Netherlands. The case study was conducted at this site and was intended to solve “order reliability” problems. While the general cause of low order reliability w...
Epileptiformic activity could result in apoptotic neuronal death, in which oxidative stress could play an important role. In case of decreased antioxidant brain status cellular death could be facilitated. Kainic acid is often used in a model of epilepsy in rats. Up to now there is not enough data evaluating levels of glutathione and nitric oxide in kainic acid-induced epilepsy acutely and sever...
BACKGROUND AND AIMS When saliva, with its high nitrite content derived from the enterosalivary recirculation of dietary nitrate, meets acidic gastric juice, the nitrite is converted to nitrous acid, nitrosative species, and nitric oxide. In healthy volunteers this potentially mutagenic chemistry is focused at the gastric cardia. We have studied the location of this luminal chemistry in Barrett'...
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