PURPOSE Nipple secretions are protein-rich and a potential source of breast cancer biomarkers for breast cancer screening. Previous studies of specific proteins have shown limited correlation with clinicopathological features. Our aim, in this pilot study, was to investigate the intra- and interpatient protein composition of nipple secretions and the implications for their use as liquid biopsie...

BACKGROUND The aim of this study was to assess the diagnostic values of three breast tumor markers (i.e., CEA, CA153 and CA125) in milk and nipple discharge in the prediction of different breast diseases diagnoses. METHODS Three hundred thirty-six patients (96 breast cancer and 240 benign disease patients) with nipple discharge and a control group of 56 healthy parturient participants were en...

Nipple-areola reconstruction is often one of the final but most challenging aspects of breast reconstruction. However, it is an integral and important component of breast reconstruction because it transforms the mound into a breast. We performed 133 nipple-areola reconstructions during a period of 4 years. Of these reconstructions, 76 of 133 nipple-areola complexes were reconstructed using the ...

there are many surgical techniques for treating gynecomastia. we report a new surgical technique in an adolescent with fatty glandular gynecomastia grade iii, who was referred from an endocrinologist to our clinic. we excised the gynecomastia with nipple repositioning utilizing the dermoglandular flap (about 1 cm thickness and 10 cm width). after one month, no complication was detected and the ...

BACKGROUND One reason for stretching before or after exercise is to reduce the risk of soreness after exercise.1 Delayed-onset muscle soreness (DOMS) typically arises within the fi rst day after exercise and peaks in intensity at around 48 h.2 This review is an update of a Cochrane review fi rst published in 2007.3 A large randomised trial (2377 participants) of both pre and postexercise stretc...

Recommended body mass index cutoff values for overweight screening programs in Australian children and adolescents: comparisons with North America values. To our knowledge, only one report describing nipple diameters in pubertal boys has been published. 1 We studied 462 boys, aged 8–17 years, to determine if nipple diameter might provide measurable criteria for assessing sexual maturation durin...

Branched-chain amino acids (BCAA) supplementation has been considered an interesting nutritional strategy to improve skeletal muscle protein turnover in several conditions. In this context, there is evidence that resistance exercise (RE)-derived biochemical markers of muscle soreness (creatine kinase (CK), aldolase, myoglobin), soreness, and functional strength may be modulated by BCAA suppleme...