In an era of escalating resistance and a lack of new antimicrobial discovery, stewardship programs must utilize knowledge of pharmacodynamics to achieve maximal exposure in the treatment of Pseudomonas aeruginosa infections. We evaluated the clinical and economic outcomes associated with extended-infusion cefepime in the treatment of P. aeruginosa infections. This single-center study compared i...

We present a new proof of Banaschewski's theorem stating that the completion lift of a uniform surjection is a surjection. The new procedure allows to extend the fact (and, similarly, the related theorem on closed uniform sublocales of complete uniform frames) to quasi-uniformities ("not necessarily symmetric uniformities"). Further, we show how a (regular) Cauchy point on a closed uniform subl...

We present in this short note a polynomial graph extension procedure that can be used to improve any graph isomorphism algorithm. This construction propagates new constraints from the isomorphism constraints of the input graphs (denoted by G(V,E) and G(V , E)). Thus, information from the edge structures of G and G is ”hashed” into the weighted edges of the extended graphs. A bijective mapping i...

in this paper, we introduce new classes $sum_{k,p,n}(alpha ,m,lambda ,l,rho )$ and $mathcal{t}_{k,p,n}(alpha ,m,lambda ,l,rho )$ of p-valent meromorphic functions defined by using the extended multiplier transformation operator. we use a strong convolution technique and derive inclusion results. a radius problem and some other interesting properties of these classes are discussed.