نتایج جستجو برای: neutrophil hyper
تعداد نتایج: 65175 فیلتر نتایج به سال:
The production of high levels of reactive oxygen species by neutrophils is associated with the local and systemic destructive phenotype found in the chronic inflammatory disease periodontitis. In the present study, we investigated the ability of sulforaphane (SFN) to restore cellular glutathione levels and reduce the hyperactivity of circulating neutrophils associated with chronic periodontitis...
Background: Mutations of ELA2, the gene encoding neutrophil elastase (NE) are known to be associated with cyclic neutropenia (CN) and severe congenital neutropenia (SCN). However, high variability of these mutations has been reported. This study was designed to describe the analysis of the ELA2 gene, clinical manifestations and demographic characteristics in patients with CN and SCN. Methods...
Hyper-heuristics are aimed at providing a generalized solution to optimization problems rather than producing the best result for one or more problem instances. This paper examines the use of evolutionary algorithm (EA) selection hyper-heuristics to solve the offline one-dimensional bin-packing problem. Two EA hyper-heuristics are evaluated. The first (EA-HH1) searches a heuristic space of comb...
BACKGROUND The onset of diabetes causes disruption of respiratory epithelial mediators. The present study investigates whether diabetes modifies the epithelium mediated bronchial responses in hyper-reactive airway smooth muscle (ASM) primarily through nitric oxide (NO), cyclooxygenase (COX), and epithelium derived hyperpolarizing factor (EpDHF) pathways. METHODS Experimental model of guinea p...
The ulcerogenic effect of corticosteroids has always been subject of controversial discussion. In this study, which is a part of another extensive study (the role of neutrophil in induction of gastric mucosal injury by different agents), the effect of prednisolone, as a widely used corticosteroid, on the rat gastric mucosa, was investigated. Prednisolone (1 mg/kg) induced acute mucosal injury (...
The present study was designed to investigate the effects of 0.0125, 0.035, 0.075 and 0.15 ppm sub-lethal concentration of copper on hematological parameters (Hb, HCT, RBC, WBC, MCV, MCH, MCHC, lymphocyte, monocyte, neutrophil and eosinophil count) of the Oncorhynchus mykiss. Samples weighted 18±3 gr and exposure to CuSo44 for a week. Physicochemical properties of water were 14±2 Cº temperature...
Many findings point to the presence of a close relationship between the immune, endocrine and neurologic systems. For example the suppressive effects of β-human chorionic gonadotropin (β-HCG) on IL-l production, the potentiative effect of enkephalins on lymphocyte functions and the suppressive effect of leuteinizing hormone (LH) on natural killer (NK) cell activities have been clearly esta...
Background The role of calcium in physiological phenomenona such as sperm acrosome reaction and hyper-activation has been well known. Calcium ionophore A23187 is routinely used for induction of acrosome reaction in mammalians sperm. Therefore, we decided to evaluate the effect of calcium ionophore A23187 on the sperm hyper-active motility patterns. MaterialsAndMethods Ten semen samples from ind...
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