Eikenella corrodens is a Gram-negative facultative anaerobe which is part of the normal human oropharyngeal flora and an opportunistic pathogen of mucous membrane tissues. We report a case of secondary E. corrodens ulcerative keratitis with hypopyon in a 39-year-old male with herpes simplex keratitis. To the best of our knowledge this is the first reported case of E. corrodens as a pathogen in ...

Background: Fungal keratitis is an acute or chronic inflammation of the cornea caused by fungi. The main treatment for fungal Natamycin 5%. Disadvantages natamycin are its poor penetration and increased resistance due to fungi which lower level ergosterol in wall. Purpose: Investigates effect bromelain, zingibain papain on LOX-1 receptors Aspergillus fumigatus. Result: receptor with bromelain p...

purpose : identifying the predisposing factors of the infectious keratitis results in understanding the underlying mechanisms of its expansion and severity that is essential for initiation of optimal empirical antimicrobial therapy. this study identified main predisposing factors of bacterial keratitis in a sample of iranian population. methods : ninety patients with bacterial keratitis were pr...

BACKGROUND The sensitivity and specificity of 18S rRNA polymerase chain reaction (PCR) in the detection of fungal aetiology of microbial keratitis was determined in thirty patients with clinical diagnosis of microbial keratitis. METHODS Corneal scrapings from patients were used for Gram stain, culture and PCR analysis. PCR was performed with primer pairs targeted to the 18S rRNA gene. The res...

OBJECTIVE Ultraviolet (UV) keratitis is a self-limited, inflammatory condition resulting in pain and temporary visual disturbance following acute UV radiation exposure. It may afflict mountaineers and other outdoor recreationalists because snow, water, and sand reflect a high percentage of UV radiation reaching the earth's surface. We examined the cases of UV keratitis that have occurred on Nat...

PURPOSE Introducing a simple image grading system to support the interpretation of in vivo confocal microscopy (IVCM) images in filamentous fungal keratitis. SETTING Clinical and confocal studies took place at the Department of Ophthalmology, Aarhus University Hospital, Denmark. Histopathological analysis was performed at the Eye Pathology Institute, Department of Neuroscience and Pharmacolog...

RATIONALE Relapsing polychondritis (RP) is a rare collagen disease characterized by inflammation and destruction of cartilage throughout the body. The paper details the clinical course of a case of RP with unique circumferential peripheral keratitis. PATIENT CONCERNS A 54-year-old Japanese woman was referred to the hospital presenting with auricular and ocular pain. DIAGNOSES Based on the a...

OBJECTIVE To evaluate the risk factors that may contribute to microbial keratitis in contact lens wearers. MATERIAL AND METHOD This prospective case-control study included 52 patients with contact lens related keratitis treated between 1 December 2006 and 15 October 2007 at the Faculty of Medicine, Siriraj Hospital. Controls were sixty-three contact lens users attending with disorders unrelat...

PURPOSE To investigate the effect of Fas and Fas ligand (FasL) deficiency on the development of herpes stromal keratitis and on the von Szily model of herpes retinitis in C57BL/6 mice, which are ordinarily resistant to development of both of these herpetic diseases. METHODS Anterior chamber inoculation of the right eye of each mouse with various titers of HSV-1 (KOS strain) was performed. Bot...