background: during the past few years, hesa-a, a herbal-marine mixture, has been used to treat cancer as an alternative medicine in iran. however, weight of the evidence is not sufficient to accept or refuse the use of this compound as a cytotoxic drug. we investigated the selective anticancer effects of hesa-a on breast, prostate, colon, and glioblastoma multiforme (gbm) neoplastic cell lines....

BACKGROUND AND PURPOSE We investigated the potential role of serum procalcitonin in differentiating tuberculosis meningitis from bacterial and viral meningitis, and in predicting the prognosis of tuberculosis meningitis. METHODS This was a retrospective study of 26 patients with tuberculosis meningitis. In addition, 70 patients with bacterial meningitis and 49 patients with viral meningitis w...

Background: Meningitis is a severe infection affecting the central nervous system requiring early management to prevent debilitating consequences and death. Detection of meningitis can be done by analysis cerebrospinal fluid cellularity biochemistry (glucose protein concentration). Urine reagent strips used assess these variables reach diagnosis early, thereby, reducing delay in initiation its ...

OBJECTIVE Lyme meningitis is difficult to differentiate from other causes of aseptic meningitis in Lyme disease-endemic regions. Parenteral antibiotics are indicated for Lyme meningitis but not viral causes of aseptic meningitis. A clinical prediction model was developed to distinguish Lyme meningitis from other causes of aseptic meningitis. Our objective was to prospectively validate this mode...

Viruses are the most common causes of aseptic meningitis. Early detection, treatment and management of viral meningitis are priority. This study aimed to evaluate common viral meningitis in children referred to Taleghani pediatrics hospital in Gorgan, south east of Caspian Sea, Iran. In this descriptive study CSF and blood samples were taken from 40 children with negative bacterial culture who ...

The use of dexamethasone in the management of bacterial meningitis in adults remains controversial. This report illustrates the case of a 27-year-old male with severe meningococcal meningitis and meningococcemia who completely recovered after receiving antibiotics and dexamethasone. In adults with suspected bacterial meningitis, especially in high risk cases, the adjunctive use of dexamethasone...

background meningitis is a life-threatening disease and can lead to significant sequelae. pediatric bacterial meningitis leaves some survivors with more significant sequelae if not treated, promptly. the advent of vaccine has changed the incidence of pediatric bacterial meningitis but these vaccines have not been used in routine childhood immunization schedule. objectives the current study aime...

Central nervous system (CNS) infection is associated with high rates of morbidity and mortality, despite advancements in molecular testing, aseptic meningitis remains challenging to diagnose. Aseptic cases are often underreported worldwide, which impacts the quality patient care. Therefore, we aimed assess results BioFire® FilmArray® meningitis/encephalitis (ME) PCR panel, clinical characterist...