Routine histological examination of the liver during the acute stages of neonatal obstructive jaundice, whether of biopsy or of autopsy specimens, reveals a variety of different pathological conditions. Congenital absence of the intrahepatic bile ducts appears to be a rare cause of obstructive jaundice in the newborn. The purpose of this paper is to draw attention to the condition by reporting ...

Peroxisome proliferator activated receptor gamma (PPARγ) is a pleiotropic ligand activated transcription factor that acts in several tissues to regulate adipocyte differentiation, lipid metabolism, insulin sensitivity and glucose homeostasis. PPARγ also regulates cardiomyocyte homeostasis and by virtue of its obligate role in placental development is required for embryonic survival. To determin...

there is an increased prevalence of maternal substance abuse during pregnancy in younger women in all socioeconomic classes and races. our aim was to determine the prevalence and correlates of self-reported substance abuse among pregnant women and obstetric complications or neonatal outcomes in iran. this retrospective cohort study is covering a five year period on medical records of pregnant w...

how to cite this article: islami z, ataee nakhaei mh. neurological manifestations of an old disease: a case report. iran j child neurol. 2013 summer; 7(3): 55-57.   objective neurological manifestations of neonatal disorders have various causes, among them neonatal tetanus, albeit rare, is a potentially fatal and preventable disease, which is seen in underdeveloped and developing countries. alt...

Neonatal injection of recombinant adeno-associated virus serotype 8 (rAAV8) vectors results in widespread transduction in multiple organs and therefore holds promise in neonatal gene therapy. On the other hand, insertional mutagenesis causing liver cancer has been implicated in rAAV-mediated neonatal gene transfer. Here, to better understand rAAV integration in neonatal livers, we investigated ...

BACKGROUND In Sweden preterm infants born <32 gestational weeks are fed maternal breastmilk or, if not available, donor breastmilk. Nutritional and immunological composition of human milk is affected by processing and storage procedures. Additionally, freezing of breastmilk may reduce cytomegalovirus transmission. The present recommendations for human milk use in Sweden are outdated. However, n...

background: neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. objective: to examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.methods: a prospective study of newborn infants hospitalized within the first 24 hours of ...