نتایج جستجو برای: negative sequence current nsc

تعداد نتایج: 1635815  

Journal: :IEEJ Transactions on Industry Applications 1993

2012
Cai-Feng Yan Shi-Jie Han Yu-Mei Zhou Cun-Guo Wang Guan-Hua Dai Wen-Fa Xiao Mai-He Li

For both ecologists and physiologists, foliar physioecology as a function of spatially and temporally variable environmental factors such as sunlight exposure within a tree crown is important for understanding whole tree physiology and for predicting ecosystem carbon balance and productivity. Hence, we studied concentrations of nitrogen (N), non-structural carbohydrates (NSC = soluble sugars + ...

Journal: :Glia 2015
Emmanuel Than-Trong Laure Bally-Cuif

The adult central nervous system (CNS) of the zebrafish, owing to its enrichment in constitutive neurogenic niches, is becoming an increasingly used model to address fundamental questions pertaining to adult neural stem cell (NSC) biology, adult neurogenesis and neuronal repair. Studies conducted in several CNS territories (notably the telencephalon, retina, midbrain, cerebellum and spinal cord...

2015
Yumei Luo Detu Zhu Dang Hoang Lam Juan Huang Yi Tang Xitu Luo Shu Wang

Recent progress in neural stem cell- (NSC-) based tumor-targeted gene therapy showed that NSC vectors expressing an artificially engineered viral fusogenic protein, VSV-G H162R, could cause tumor cell death specifically under acidic tumor microenvironment by syncytia formation; however, the killing efficiency still had much room to improve. In the view that coexpression of another antitumoral g...

2016
Jieun Jung Jong-Wan Kim Ho-Jin Moon Jin Young Hong Jung Keun Hyun

Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study, we selectively e...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
Zhengliang Gao Kerstin Ure Peiguo Ding Mostafa Nashaat Laura Yuan Jing Ma Robert E Hammer Jenny Hsieh

Transcriptional regulation is a critical mechanism in the birth, specification, and differentiation of granule neurons in the adult hippocampus. One of the first negative-acting transcriptional regulators implicated in vertebrate development is repressor element 1-silencing transcription/neuron-restrictive silencer factor (REST/NRSF)--thought to regulate hundreds of neuron-specific genes--yet i...

Journal: :AAPS PharmSciTech 2012

Journal: :American journal of cancer research 2017
Zijun Zhen Kaibin Yang Litong Ye Zhiyao You Rirong Chen Ying Liu Youjian He

Neuroblastoma stem cells (NSCs) can cause drug resistance and tumor recurrence. This study aimed to enhance the lytic effect of dendritic cells (DCs) co-cultured with cytokine-induced killer (CIK) cells. NSCs were obtained by suspension culture, and DC-CIK cells were loaded with extracted NSC membrane-based microparticles (MMPs) before evaluating the lytic effect of DC-CIK cells on NSCs. After ...

2008
Shuliang Wu Akira Sasaki Reiko Yoshimoto Yumi Kawahara Tomotaka Manabe Katsuko Kataoka Makoto Asashima Louis Yuge

Objective: We investigated whether neural stem cells (NSC) with transgenic expression of human nerve growth factor (hNGF) transplanted into the brain could offer a therapeutic option for the treatment of Alzheimer’s disease (AD). Methods: We infused okadaic acid into rat lateral ventricles to establish a chronic AD animal model. In addition, NSC were stably transduced with hNGF and enhanced gre...

Journal: :Genes & development 2008
Yechiel Elkabetz Georgia Panagiotakos George Al Shamy Nicholas D Socci Viviane Tabar Lorenz Studer

Neural stem cells (NSCs) yield both neuronal and glial progeny, but their differentiation potential toward multiple region-specific neuron types remains remarkably poor. In contrast, embryonic stem cell (ESC) progeny readily yield region-specific neuronal fates in response to appropriate developmental signals. Here we demonstrate prospective and clonal isolation of neural rosette cells (termed ...

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