BACKGROUND Digital nerve block is commonly performed by care providers in medical fields. This study compares the blocks in terms of effectiveness of anesthesia and pain. METHODS Patients were divided into two groups. First group underwent digital block whereas 2nd group had transmetacarpal digital block. The subcutaneous ring block was performed by two injections of 3 ml of 2% lignoca...

Administration of insulin via a pen device may be advantageous over a vial and syringe system. Hofman and colleagues introduce a new insulin pen needle, the NovoTwist, to simplify injections to a small group of children and adolescents. Their overall preferences and evaluation of the handling of the needle are reported in the study. This new needle has the potential to ease administration of in...

BACKGROUND Over 14 million people die each year from infectious diseases despite extensive vaccine use [1]. The needle and syringe--first invented in 1853--is still the primary delivery device, injecting liquid vaccine into muscle. Vaccines could be far more effective if they were precisely delivered into the narrow layer just beneath the skin surface that contains a much higher density of pote...

Hepatic sinusoids of human liver samples obtained by surgical or needle biopsy were examined under the scanning and transmission electron microscopes (SEM and TEM). The surgically obtained tissues were perfused, by the use of a needle and syringe, with Ringer solution and successively with glutaraldehyde solution through the cut ends of blood vessels, while the needle biopsy pieces were perfuse...