The gross and histopathological lesions of 10 cases in a natural outbreak of aflatoxicosis amongst dogs in the Republic of South Africa are reported. The 10 cases were classified as acute (1 case), subacute (7 cases) and chronic (2 cases) on the basis of the nature, degree and extent of the following histopathological fractures: hepatocellular fatty degeneration, necrosis or regeneration; proli...

Background: Repairing the burn-injury induced cell death and improving wound healing are critical issues. Objectives: This study was focused on assessment of hydroxychloroquine (HCQ)- recovered burn injury in vivo vitro models. Materials & Methods: In this study, we constructed animal models second-degree burns, showed that heating at 55 Celsius degree for 5 min caused skin cells to switch from...

An intravenous mouse infection model was used to compare the virulence of Enterococcus faecalis strains, to study bacterial localization and organ histopathology, and to examine the effects of Nramp1 and gamma interferon (IFN-gamma) on the course of infection. Infection of BALB/c mice with 5 x 10(8) CFU of E. faecalis JH2-2, MGH-2, 418, DS16C2, or OG1X revealed the following virulence ranking (...

BACKGROUND Lung ultrasonography has been advocated in diagnosing pediatric community-acquired pneumonia. However, its function in identifying necrotizing pneumonia, a complication, has not been explored. This study investigated the value of lung ultrasonography in diagnosing pediatric necrotizing pneumonia and its role in predicting clinical outcomes. METHODS We retrospectively reviewed 236 c...

To explore the effect of health education model based on behavior change wheel (BCW) theory in patients with acute retinal necrosis (ARN). 78 diagnosed ARN were randomly divided into control group (n = 39) and observation 39). The received standard eye care, whereas was given BCW theory-based care. two groups compared uncertainty disease, anxiety depression levels, treatment compliance, disease...

Background: The widely adopted Jablonski scoring system for reporting histological damage in kidney ischaemia reperfusion injury (IRI) provides a limited score documenting the degree of necrosis within tubular cells. IRI is a complex process that involves damage to various cellular components of the renal cortex and therefore there is a need to develop a more detailed scoring system. The aims o...

  Objective(s): The aim of this study was to evaluate the effect of subacute administration of propylthiouracil (PTU) on gentamicin (GM)-induced nephrotoxicity in male rats.   Materials and Methods: Male Wistar rats were divided into 4 experimental groups as follow: (1) Control group: isotonic saline (1 ml/kg, IP. for 18 d), (2) GM group: 100 mg/kg, IP for 8 d, (3) PTU group: PTU...

objective(s): the aim of this study was to evaluate the effect of subacute administration of propylthiouracil (ptu) on gentamicin (gm)-induced nephrotoxicity in male rats.   materials and methods: male wistar rats were divided into 4 experimental groups as follow: (1) control group: isotonic saline (1 ml/kg, ip. for 18 d), (2) gm group: 100 mg/kg, ip for 8 d, (3) ptu group: ptu (10 mg/kg, ip fo...