A 18-year-old male patient's case was diagnosed as Degos'disease with pathognomonic skin lesions, accompanied by small bowel perforation, and reported here. Skin histopothological test show that the typical wedge-shaped necrobiosis and lymphocyte inflammatory infiltration. Vessels showed narrowing and thrombosis, with lymphocyte infiltration. Degos' disease is a systemic necrotizing vasculitis....

A culture consists of a plasmatic medium inoculated with small fragments of living tissues. It is essentially characterized by an active growth of the ceils from the original fragment into the plasmatic medium. Epithelial or connective tissue cells wander out in great number from the tissue into the coagulated plasma where they undergo direct or indirect divisions. They cover a wide area of the...

OBJECTIVE It is yet unknown the relationship between diabetes and determinants or triggering factors of skin lesions in diabetic patients. The purpose of the present study was to investigate the presence of unreported skin lesions in diabetic patients and their relationship with metabolic control of diabetes. METHODS A total of 403 diabetic patients, 31% type 1 and 69% type 2, underwent derma...

Introduction. Adenomyosis is a widespread disease usually affecting the late reproductive years of the women's life, which has a great impact on their fertility. The most common form is diffuse adenomyosis, while focal adenomyosis, a cystic variant, is very rare, particularly in patients younger than 30 years old. Materials and methods. We reported a rare case of a 20-year-old Caucasian woman w...

Granuloma multiforme (GM) is a reactive skin disorder of unknown etiology, characterized clinically by confluent annular lesions and histologically by focal necrobiosis and histiocytic granulomas. GM is significant because of its clinical resemblance to tuberculoid leprosy, with which it can be confused. Here, we report a case of granuloma multiforme from India in a 70-year-old male farmer, wit...

Necrobiotic xanthogranuloma (NXG) is a rare systemic disease primarily associated with cutaneous plaques; these plaques can manifest anywhere, but most commonly affect the face and periorbital regions. It has a distinct histopathology with extensive necrobiosis and infiltrates of inflammatory cells. Patients with NXG are often found to have paraproteinemia or hematologic disorders, including mu...

I t has been shown that a single intracutaneous injection of autologous or homologous spermia, or testicular suspension incorporated in a water-in-oil emulsion containing killed mycobacteria, induces aspermatogenesis in the guinea pig (1). This process results in the degeneration, necrobiosis, and elimination of most of the germinal cells without injury to the Leydig cells or accessory genital ...