administration of endotracheal surfactant is potentially the main treatment for neonates suffering from rds (respiratory distress syndrome), which is followed by mechanical ventilation. late and severe complications may develop as a consequence of using mechanical ventilation. in this study, conventional methods for treatment of rds are compared with surfactant administration, use of mechanical...

introduction respiratory distress syndrome (rds) is a current cause of morbidity in premature infants resulted from surfactant deficiency. the primary aim of this randomized study was to describe the feasibility of early administration of surfactant via a thin catheter during spontaneous breathing (tec) and compare its outcomes with the insure (intubate, surfactant, extubate) procedure material...

background: in recent years, various noninvasive respiratory support (nrs) of ventilation has been provided more in neonates. the aim of this study was to compare the effect of hfnc with ncpap in post-extubation of preterm infants with rds after insure method (intubation, surfactant, extubation). methods: a total of 54 preterm infants with rds (respiratory distress syndrome) were enrolled in th...

Patients with insomnia may develop suicidal ideation; however, we know of no reports of suicidal ideation associated with obstructive sleep apnea. We report on a 74-year-old man who presented to his primary care physician with excessive daytime sleepiness, poor quality nocturnal sleep, depressed mood and suicidal ideation with active suicide plans. An emergency outpatient psychiatry consultatio...

Bronchopulmonary dysplasia (BPD), also known as chronic lung disease (CLD), is the most common serious morbidity associated with premature birth, particularly among those infants who have respiratory distress syndrome (RDS) and receive mechanical ventilation after birth. BPD is characterized by lung inflammation and scarring, which are thought to be the effects of excessive (or inadequate) vent...

Right This is the peer reviewed version of the following article: Ishihara, C., Ibara, S., Ohsone, Y., Kato, E., Tokuhisa, T., Yamamoto, Y., Maede, Y., Kuwahara, T., and Minakami, H. (2016) Effects of infant flow Bi-NCPAP on apnea of prematurity. Pediatrics International, 58: 456‒460, which has been published in final form at http://dx.doi.org/10.1111/ped.12854. This article may be used for non...

The association between sleep-disordered breathing (SDB) and stroke cannot be attributed to chance. Indeed, if a link between SDB and cardiovascular disease were demonstrated [1–5], the absence of a relationship with stroke would be surprising. Although we still lack definitive and consistent data from large epidemiological surveys, multiple studies using a variety of methodologies have shown a...

We conducted this study to investigate the efficacy of the silicon gel application on the nares in prevention of nasal injury in preterm infants ventilated with nasal continuous positive airway pressure (NCPAP). Patients (n=179) were randomized into two groups: Group 1 (n=87) had no silicon gel applied to nares, and in Group 2 (n=92), the silicon gel sheeting was used on the surface of nares du...

Mandibuloacral dysplasia (MAD; MIM 248370, 608612) is a rare progeroid syndrome with autosomal recessive inheritance. It is characterized by mandibular hypoplasia, acroosteolysis, delayed closure of the cranial sutures, skin atrophy with mottled hyperpigmentation, stiff joints, and growth retardation. We here report Japanese female siblings with a severe MAD phenotype. Because of extreme microg...