Abstract: Background: Hepato-Renal impairment refers to renal dysfunction in a liver compromised state concerning lead metal exposure. Natural chelators (marine source) have potent chelating properties claiming ameliorate hepato-renal heavy toxicity Material and Methods: A total of 42 male albino Wistar rats weighing between 200 250 g were categorised into seven groups (n=6). Except for the fir...

The objective of this study was to explore work-related risk factors of acute occupational pesticide poisoning among male farmers according to the severity of the poisoning. A nationwide sampling survey of male farmers was conducted in South Korea in 2011. A total of 1,958 male farmers were interviewed. Severity of occupational pesticide poisoning in 2010 was evaluated according to symptoms, ty...

OBJECTIVE To develop a flowchart to be used as a tool to guide clinicians step by step through the management of salicylate poisoning. METHODS A comprehensive literature search was carried out. RESULTS The evidence base was used to develop a management flowchart that guides the clinician through the three main steps in caring for the patient with salicylate poisoning: preventing further abs...

It is well known that children < 7 years of age are uniquely susceptible to lead poisoning because of their constant hand-to-mouth behaviors, their immature central nervous systems, and their rapidly developing bodies (Gavaghan 2002; Lanphear et al. 2005; Shen 1996; Tong et al. 1996, 1998). Although exposure to lead has decreased in many countries, significant concerns remain about continued ex...

The authors analyzed over 200 cases of acute poisoning with sarin, soman and VX chemical, determined risk of the poisoning in various conditions. The clinical manifestations of acute poisoning and the long-term effects are presented.

The trends in self-poisoning rates and in rates of prescribing of the major drug groups were compared. Over the period 1981-91, barbiturate prescribing and self poisoning both fell by 80%; for antidepressants, prescribing increased by over 40% and self poisoning by 30%; for antipsychotics, both rose by 30%; for benzodiazepines, poisoning fell by 30% and prescribing by 20%. Even for analgesic dr...

1. Collagenolytic activity towards acid-soluble collagen labelled with [(14)C]-proline was assayed in rat liver with and without carbon tetrachloride poisoning. The products of enzymic digestion were found to be free amino acids and peptides. 2. The hepatic collagenolytic activity increased under conditions of single-dose and subacute carbon tetrachloride poisoning, and correlated with hydroxyp...

background: poisoning is one of the important reasons for children’s admission to hospital. knowledge of epidemiology of poisoning in each region plays an important role in planning prevention, care, and treatment of patients. this study was conducted to determine the characteristics of acute poisoning epidemiology in children attending pediatric wards of amirkabir hospital in arak in a five-ye...